Beneficial effects of environmental enrichment on behavior, stress reactivity and synaptophysin/BDNF expression in hippocampus following early life stress
Ε Dandi, A Kalamari, O Touloumi, R Lagoudaki… - International Journal of …, 2018 - Elsevier
Exposure to environmental enrichment can beneficially influence the behavior and enhance
synaptic plasticity. The aim of the present study was to investigate the mediated effects of …
synaptic plasticity. The aim of the present study was to investigate the mediated effects of …
Enriched environment treatment restores impaired hippocampal synaptic plasticity and cognitive deficits induced by prenatal chronic stress
J Yang, C Hou, N Ma, J Liu, Y Zhang, J Zhou… - Neurobiology of learning …, 2007 - Elsevier
Prenatal stress can cause long-term effects on cognitive functions in offspring. Hippocampal
synaptic plasticity, believed to be the mechanism underlying certain types of learning and …
synaptic plasticity, believed to be the mechanism underlying certain types of learning and …
Postweaning enriched environment enhances cognitive function and brain-derived neurotrophic factor signaling in the hippocampus in maternally separated rats
Adverse environments during early life may lead to different neurophysiological and
behavioral consequences, including depression and learning and memory deficits that …
behavioral consequences, including depression and learning and memory deficits that …
Neurobiological effects of neonatal maternal separation and post-weaning environmental enrichment
Throughout the lifespan, the brain has a considerable degree of plasticity and can be
strongly influenced by sensory input from the outside environment. Given the importance of …
strongly influenced by sensory input from the outside environment. Given the importance of …
Enriched environment experience overcomes the memory deficits and depressive-like behavior induced by early life stress
M Cui, Y Yang, J Yang, J Zhang, H Han, W Ma, H Li… - Neuroscience …, 2006 - Elsevier
Stress in early life is believed to cause cognitive and affective disorders, and to disrupt
hippocampal synaptic plasticity in adolescence into adult, but it is unclear whether exposure …
hippocampal synaptic plasticity in adolescence into adult, but it is unclear whether exposure …
Maternal separation of rat pups increases the risk of developing depressive-like behavior after subsequent chronic stress by altering corticosterone and neurotrophin …
L Marais, SJ Van Rensburg, JM Van Zyl, DJ Stein… - Neuroscience …, 2008 - Elsevier
Children that are abused have an increased risk for developing psychiatric disorders later in
life, because of the negative effects of stress on the developing brain. We used a maternal …
life, because of the negative effects of stress on the developing brain. We used a maternal …
Social isolation and social support at adulthood affect epigenetic mechanisms, brain-derived neurotrophic factor levels and behavior of chronically stressed rats
JV Borges, BS de Freitas, V Antoniazzi… - Behavioural brain …, 2019 - Elsevier
Epigenetic modulation of brain-derived neurotrophic factor (BDNF) provides one possible
explanation for the dysfunctions induced by stress, such as psychiatric disorders and …
explanation for the dysfunctions induced by stress, such as psychiatric disorders and …
Differential neuronal plasticity in mouse hippocampus associated with various periods of enriched environment during postnatal development
S Hosseiny, M Pietri, A Petit-Paitel, H Zarif… - Brain Structure and …, 2015 - Springer
Enriched environment (EE) is characterized by improved conditions for enhanced
exploration, cognitive activity, social interaction and physical exercise. It has been shown …
exploration, cognitive activity, social interaction and physical exercise. It has been shown …
Effects of neonatal stress on markers of synaptic plasticity in the hippocampus: implications for spatial memory
B Aisa, N Elizalde, R Tordera, B Lasheras… - …, 2009 - Wiley Online Library
Early stressful adverse situations may increase the vulnerability to cognitive deficits and
psychiatric disorders, such as depression. Maternal separation (MS) has been used as an …
psychiatric disorders, such as depression. Maternal separation (MS) has been used as an …
Effects of enriched environment on depression and anxiety-like behavior induced by early life stress: a comparison between different periods
H Huang, Q Wang, X Guan, X Zhang, Y Zhang… - Behavioural Brain …, 2021 - Elsevier
Background Brain development is a prolonged process and it is sensitive to the environment
during critical periods. Stress in early life is believed to increase vulnerability to depression …
during critical periods. Stress in early life is believed to increase vulnerability to depression …