The promise of DNA methylation in understanding multigenerational factors in autism spectrum disorders

JS Mouat, JM LaSalle - Frontiers in Genetics, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized
by impairments in social reciprocity and communication, restrictive interests, and repetitive …

DNA methylation and susceptibility to autism spectrum disorder

MW Tremblay, Y Jiang - Annual review of medicine, 2019 - annualreviews.org
The prevalence of autism spectrum disorder (ASD) has been increasing steadily over the
last 20 years; however, the molecular basis for the majority of ASD cases remains unknown …

Future prospects for epigenetics in autism spectrum disorder

LA Williams, JM LaSalle - Molecular Diagnosis & Therapy, 2022 - Springer
Despite decades of investigation into the genetics of autism spectrum disorder (ASD), a
current consensus in the field persists that ASD risk is too heterogeneous to be diagnosed …

Common DNA methylation alterations in multiple brain regions in autism

C Ladd-Acosta, KD Hansen, E Briem, MD Fallin… - Molecular …, 2014 - nature.com
Autism spectrum disorders (ASD) are increasingly common neurodevelopmental disorders
defined clinically by a triad of features including impairment in social interaction, impairment …

Genetics of autism spectrum disorders and future direction

Y Yasuda, J Matsumoto, K Miura… - Journal of Human …, 2023 - nature.com
Autism spectrum disorders (ASDs) have been increasing in prevalence. ASD is a complex
human genetic disorder with high heredity and involves interactions between genes and the …

Epigenomic signatures reveal mechanistic clues and predictive markers for autism spectrum disorder

JM LaSalle - Molecular psychiatry, 2023 - nature.com
Autism spectrum disorder (ASD) comprises a heterogeneous group of neurodevelopmental
outcomes in children with a commonality in deficits in social communication and language …

The epigenetics of autism

A Massrali, V Warrier, A Paul, D Adhya… - Chromatin Signaling …, 2019 - Elsevier
Autism spectrum conditions (ASCs) are neurodevelopmental in origin and entail social-
communication disability alongside unusually narrow interests and difficulties adjusting to …

Elevated polygenic burden for autism is associated with differential DNA methylation at birth

E Hannon, D Schendel, C Ladd-Acosta, J Grove… - Genome medicine, 2018 - Springer
Background Autism spectrum disorder (ASD) is a severe neurodevelopmental disorder
characterized by deficits in social communication and restricted, repetitive behaviors …

Autism-associated DNA methylation at birth from multiple tissues is enriched for autism genes in the early autism risk longitudinal investigation

KM Bakulski, JF Dou, JI Feinberg, MT Aung… - Frontiers in Molecular …, 2021 - frontiersin.org
Background: Pregnancy measures of DNA methylation, an epigenetic mark, may be
associated with autism spectrum disorder (ASD) development in children. Few ASD studies …

DNA Methylation Biomarkers for Young Children with Idiopathic Autism Spectrum Disorder: A Systematic Review

A Stoccoro, E Conti, E Scaffei, S Calderoni… - International journal of …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition, the underlying
pathological mechanisms of which are not yet completely understood. Although several …