There is a paucity of information concerning the developmental neurotoxicity (DNT) hazard
posed by industrial and environmental chemicals. New testing approaches will most likely …

Developmental neurotoxicity testing (DNT) is perceived by many stakeholders to be an area
in critical need of alternative methods to current animal testing protocols and guidelines. An …

Abstract The Organisation for Economic Co-Operation and Development (OECD)
coordinates international efforts to enhance developmental neurotoxicity (DNT) testing. In …

This consensus statement voices the agreement of scientific stakeholders from regulatory
agencies, academia and industry that a new framework needs adopting for assessment of …

A key trait of developmental neurotoxicants is their ability to cause structural lesions in the
immature nervous system. Thus, neuropathologic assessment is an essential element of …

The goal of this systematic review performed under a contract with EFSA was the evaluation
of information on assessment methods in the field of developmental neurotoxicity (DNT) …

Currently, the identification of chemicals that have the potential to induce developmental
neurotoxicity (DNT) is based on animal testing. Since at the regulatory level, systematic …

Simple Summary It is recognized that the current developmental neurotoxicity (DNT) testing
paradigm is not fit-for-purpose for the assessment of a large number of chemicals. In the last …

Conference Reports test Guidelines OPPtS 8706300 on DNt (US ePA, 1998) and in 2007
the Organization for economic Cooperation and Development (OeCD) endorsed a new …

Environmental chemicals have a potential impact on children's health as the developing
brain is much more vulnerable to injury caused by different classes of chemicals than the …