Premedication with oral and transdermal clonidine provides safe and efficacious postoperative sympatholysis

JE Ellis, G Drijvers, S Pedlow, SP Laff… - Anesthesia & …, 1994 - journals.lww.com
We studied 61 patients undergoing elective major non-cardiac surgery in a randomized,
double-blind, placebo-control clinical trial to test the hypothesis that the addition of clonidine …

Oral clonidine pretreatment prior to venous cannulation

DL Hall, E Rezvan, DN Tatakis… - Anesthesia …, 2006 - meridian.allenpress.com
Clonidine is a preferential alpha-2 agonist drug that has been used for over 35 years to treat
hypertension. Recently, it has also been used as a preoperative medication and as a …

Preserved Sympathetic Response to Hypotension Despite Perioperative alpha (2) Agonist Administration

JM Dodd-o, MJ Breslow, T Dorman… - Anesthesia & …, 1997 - journals.lww.com
Preserved Sympathetic Response to Hypotension Despite Periop... : Anesthesia &
Analgesia Preserved Sympathetic Response to Hypotension Despite Perioperative alpha (2) …

Clonidine and modification of perioperative outcome

AW Wallace - Current Opinion in Anesthesiology, 2006 - journals.lww.com
Administration of perioperative clonidine can reduce the risk of perioperative myocardial
ischemia and mortality in patients undergoing non-cardiac surgery. Perioperative clonidine …

Comparison of nicardipine versus placebo to control hemodynamic responses during emergence and extubation

AL Kovac, C McKinley, CJ Tebbe, C Williams - Journal of cardiothoracic …, 2001 - Elsevier
Objective: To compare 2 different doses of intravenous nicardipine versus placebo to control
heart rate and blood pressure responses to emergence and extubation. Design …

Oral clonidine premedication reduces the awakening concentration of isoflurane

T Goyagi, M Tanaka, T Nishikawa - Anesthesia & Analgesia, 1998 - journals.lww.com
Because clonidine has analgesic and sedative properties, it may influence the awakening
concentration or dose of an anesthetic. To investigate the effects of oral clonidine …

Intravenous clonidine fails to reduce postoperative meperidine requirements

WH Striebel, DI Koenigs, JA Kramer - Journal of clinical anesthesia, 1993 - Elsevier
Abstract Study Objective: To investigate the effect of an additional postoperative intravenous
(IV) clonidine infusion on meperidine requirements in the early postoperative period …

Oral clonidine premedication exacerbates hypotension following tourniquet deflation by inhibiting noradrenaline release

K Maruyama, S Takeda, T Hongo… - Journal of Nippon …, 2004 - jstage.jst.go.jp
Clonidine premedication prevents tourniquet pain and reduces sympathetic nerve activity.
We evaluated hemodynamic changes and catecholamine release following tourniquet …

The effect of clonidine on perioperative blood coagulation

MT Ganter, CK Hofer, DR Spahn, M Bruggisser… - Journal of clinical …, 2005 - Elsevier
STUDY OBJECTIVE: To evaluate the influence of perioperative stress protection by
clonidine on blood coagulation. DESIGN: Prospective, randomized, double-blinded, placebo …

Effect of peri-operative intravenous infusion of lignocaine on haemodynamic responses to intubation, extubation and post-operative analgesia

S Jain, RM Khan - Indian journal of anaesthesia, 2015 - journals.lww.com
Methods: In this randomised prospective study, 60 patients undergoing elective
laparoscopic cholecystectomy were randomly divided into two groups of 30 each. In Group …