Biology of cerebral arteriovenous malformations with a focus on inflammation

N Mouchtouris, PM Jabbour… - Journal of Cerebral …, 2015 - journals.sagepub.com
Cerebral arteriovenous malformations (AVMs) entail a significant risk of intracerebral
hemorrhage owing to the direct shunting of arterial blood into the venous vasculature …

Neurovascular inflammation in the pathogenesis of brain arteriovenous malformations

S Krithika, S Sumi - Journal of Cellular Physiology, 2021 - Wiley Online Library
Brain arteriovenous malformations (bAVM) arise as congenital or sporadic focal lesions with
a significant risk for intracerebral hemorrhage (ICH). A wide range of interindividual …

Brain arteriovenous malformation biology relevant to hemorrhage and implication for therapeutic development

H Kim, L Pawlikowska, Y Chen, H Su, GY Yang… - Stroke, 2009 - Am Heart Assoc
Brain arteriovenous malformations cause intracranial hemorrhage. Molecular
characterization of lesional tissue implicates angiogenic (vascular endothelial growth factor …

Cerebral arteriovenous malformations. Part 1: cellular and molecular biology

P Moftakhar, JS Hauptman, D Malkasian… - Neurosurgical focus, 2009 - thejns.org
Object The scientific understanding of the nature of arteriovenous malformations (AVMs) in
the brain is evolving. It is clear from current work that AVMs can undergo a variety of …

[图书][B] Vascular integrity in the pathogenesis of brain arteriovenous malformation

R Zhang, W Zhu, H Su - 2016 - Springer
Brain arteriovenous malformation (bAVM) is an important cause of intracranial hemorrhage
(ICH), particularly in the young population. ICH is the first clinical symptom in about 50% of …

Cerebral arteriovenous malformations. Part 2: physiology

P Moftakhar, JS Hauptman, D Malkasian… - Neurosurgical focus, 2009 - thejns.org
Object The scientific understanding of the nature of arteriovenous malformations (AVMs) in
the brain is evolving. It is clear from current work that AVMs can undergo a variety of …

Molecular and cellular biology of cerebral arteriovenous malformations: a review of current concepts and future trends in treatment

L Rangel-Castilla, JJ Russin, E Martinez-del-Campo… - Neurosurgical …, 2014 - thejns.org
Object Arteriovenous malformations (AVMs) are classically described as congenital static
lesions. However, in addition to rupturing, AVMs can undergo growth, remodeling, and …

Evidence of inflammatory cell involvement in brain arteriovenous malformations

Y Chen, W Zhu, AW Bollen, MT Lawton… - …, 2008 - journals.lww.com
OBJECTIVE: Brain arteriovenous malformations (AVM) have high matrix metalloproteinase-
9, interleukin-6, and myeloperoxidase (MPO) expression, and polymorphic variations in …

Persistent infiltration and pro-inflammatory differentiation of monocytes cause unresolved inflammation in brain arteriovenous malformation

R Zhang, Z Han, V Degos, F Shen, EJ Choi, Z Sun… - Angiogenesis, 2016 - Springer
An abnormally high number of macrophages are present in human brain arteriovenous
malformations (bAVM) with or without evidence of prior hemorrhage, causing unresolved …

[图书][B] Brain arteriovenous malformation pathogenesis: a response-to-injury paradigm

H Kim, H Su, S Weinsheimer, L Pawlikowska… - 2011 - Springer
Brain arteriovenous malformations (AVMs) are a rare but important cause of intracranial
hemorrhage (ICH) in young adults. In this paper, we review both human and animal studies …