Hereditary spastic paraplegias (HSP) are a group of genetically and clinically
heterogeneous neurologic disorders. Hereby we describe a relatively large group of patients …

Hereditary spastic paraplegias (HSP) are a large group of genetic diseases characterized by
progressive degeneration of the long tracts of the spinal cord, namely the corticospinal tracts …

Purpose To investigate whether specific patterns of brain gray matter (GM) regional volumes
and white matter (WM) microstructural abnormalities and spinal cord atrophy occur in …

Introduction Hereditary spastic paraplegias (HSP) include a clinically and genetically
heterogeneous group of conditions. Novel imaging modalities have been increasingly …

Hereditary spastic paraplegias (HSP) are a group of clinically and genetically
heterogeneous disorders with the hallmark of progressive spastic gait disturbance. We used …

Hereditary spastic paraparesis (HSP) is a heterogeneous group of neurodegenerative
disorders with progressive lower limb spasticity, categorized into pure (p‐HSP) and …

Background Hereditary Spastic Paraplegias (HSP) are genetic neurodegenerative disorders
affecting the corticospinal tract. No established neuroimaging biomarker is associated with …

To determine the cortical mechanism that underlies the cognitive impairment and motor
disability in hereditary spastic paraplegia (HSP), nine HSP patients from a Chinese family …

Hereditary spastic paraplegias (HSPs) are a clinically and genetically heterogeneous group
of neurodegenerative disorders characterized by progressive spasticity and weakness of the …

Background Hereditary spastic paraplegias (HSP) are a composite and genetically
heterogeneous group of conditions mainly expressed by the impairment of the central motor …