Genetic and early environmental influences on the serotonin system: consequences for brain development and risk for psychopathology
Background: Despite more than 60 years of research in the role of serotonin (5-HT) in
psychopathology, many questions still remain. From a developmental perspective, studies …
psychopathology, many questions still remain. From a developmental perspective, studies …
Developmental changes in serotonin signaling: Implications for early brain function, behavior and adaptation
S Brummelte, E Mc Glanaghy, A Bonnin, TF Oberlander - Neuroscience, 2017 - Elsevier
Abstract The neurotransmitter serotonin (5-HT) plays a central role in brain development,
regulation of mood, stress reactivity and risk of psychiatric disorders, and thus alterations in …
regulation of mood, stress reactivity and risk of psychiatric disorders, and thus alterations in …
Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation
S Migliarini, G Pacini, B Pelosi, G Lunardi… - Molecular …, 2013 - nature.com
Despite increasing evidence suggests that serotonin (5-HT) can influence neurogenesis,
neuronal migration and circuitry formation, the precise role of 5-HT on central nervous …
neuronal migration and circuitry formation, the precise role of 5-HT on central nervous …
[HTML][HTML] Gestational factors throughout fetal neurodevelopment: the serotonin link
SI Hanswijk, M Spoelder, L Shan, MMM Verheij… - International journal of …, 2020 - mdpi.com
Serotonin (5-HT) is a critical player in brain development and neuropsychiatric disorders.
Fetal 5-HT levels can be influenced by several gestational factors, such as maternal …
Fetal 5-HT levels can be influenced by several gestational factors, such as maternal …
Fetal serotonin signaling: setting pathways for early childhood development and behavior
TF Oberlander - Journal of Adolescent Health, 2012 - Elsevier
Finely tuning levels of the key neurotransmitter serotonin (5-hydroxytryptamine [5-HT])
during early life is essential for brain development and setting pathways for health and …
during early life is essential for brain development and setting pathways for health and …
[HTML][HTML] Abnormal serotonin levels during perinatal development lead to behavioral deficits in adulthood
R Shah, E Courtiol, FX Castellanos… - Frontiers in behavioral …, 2018 - frontiersin.org
Serotonin (5-HT) is one of the best-studied modulatory neurotransmitters with ubiquitous
presynaptic release and postsynaptic reception. 5-HT has been implicated in a wide variety …
presynaptic release and postsynaptic reception. 5-HT has been implicated in a wide variety …
The Developmental Basis of Epigenetic Regulation of HTR2A and Psychiatric Outcomes
AG Paquette, CJ Marsit - Journal of Cellular Biochemistry, 2014 - Wiley Online Library
The serotonin receptor 5‐HT2A (encoded by HTR2A) is an important regulator of fetal brain
development and adult cognitive function. Environmental signals that induce epigenetic …
development and adult cognitive function. Environmental signals that induce epigenetic …
Serotonin, genetic variability, behaviour, and psychiatric disorders-a review
N Nordquist, L Oreland - Upsala journal of medical sciences, 2010 - Taylor & Francis
Brain monoamines, and serotonin in particular, have repeatedly been shown to be linked to
different psychiatric conditions such as depression, anxiety, antisocial behaviour, and …
different psychiatric conditions such as depression, anxiety, antisocial behaviour, and …
[HTML][HTML] Refining the role of 5-HT in postnatal development of brain circuits
Changing serotonin (5-hydroxytryptamine, 5-HT) brain levels during critical periods in
development has long-lasting effects on brain function, particularly on later …
development has long-lasting effects on brain function, particularly on later …
Sex differences in response to chronic mild stress and congenital serotonin deficiency
Women exhibit a nearly twofold increased risk of developing depression and anxiety
disorders when compared to men, a fact that has been hypothesized to result in part from …
disorders when compared to men, a fact that has been hypothesized to result in part from …