Hippocampal atrophy subtypes of Alzheimer's disease using automatic MRI in a memory clinic cohort: clinical implications

K Persson, TH Edwin, AB Knapskog… - Dementia and geriatric …, 2022 - karger.com
Introduction: One pathological hallmark of Alzheimer's disease (AD) is atrophy of medial
temporal brain regions that can be visualized on magnetic resonance imaging (MRI), but not …

Neuroimaging of hippocampal atrophy in early recognition of Alzheimer´ s disease–a critical appraisal after two decades of research

J Schröder, J Pantel - Psychiatry Research: Neuroimaging, 2016 - Elsevier
As a characteristic feature of Alzheimer´ s disease (AD) hippocampal atrophy (HA) can be
demonstrated in the majority of patients by using neuroimaging techniques in particular …

Distinct subtypes of Alzheimer's disease based on patterns of brain atrophy: longitudinal trajectories and clinical applications

D Ferreira, C Verhagen, JA Hernández-Cabrera… - Scientific reports, 2017 - nature.com
Atrophy patterns on MRI can reliably predict three neuropathological subtypes of
Alzheimer's disease (AD): typical, limbic-predominant, or hippocampal-sparing. A method to …

MRI-assessed atrophy subtypes in Alzheimer's disease and the cognitive reserve hypothesis

K Persson, RS Eldholm, ML Barca, L Cavallin… - PLoS …, 2017 - journals.plos.org
Background/Aims MRI assessment of the brain has demonstrated four different patterns of
atrophy in patients with Alzheimer's disease dementia (AD): typical AD, limbic-predominant …

Alzheimer disease brain atrophy subtypes are associated with cognition and rate of decline

SL Risacher, WH Anderson, A Charil, PF Castelluccio… - Neurology, 2017 - AAN Enterprises
Objective: To test the hypothesis that cortical and hippocampal volumes, measured in vivo
from volumetric MRI (vMRI) scans, could be used to identify variant subtypes of Alzheimer …

[HTML][HTML] Regional patterns of atrophy on MRI in Alzheimer's disease: Neuropsychological features and progression rates in the ADNI cohort

R Duara, DA Loewenstein, Q Shen, W Barker… - Advances in Alzheimer's …, 2013 - scirp.org
Background: Discrete clinical and pathological subtypes of Alzheimer's disease (AD) with
variable presentations and rates of progression are well known. These subtypes may have …

Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia

CR Jack Jr, DW Dickson, JE Parisi, YC Xu, RH Cha… - Neurology, 2002 - AAN Enterprises
Objectives: To assess the diagnostic specificity of MRI-defined hippocampal atrophy for AD
among individuals with a variety of pathologically confirmed conditions associated with …

Early diagnosis of Alzheimer's disease: contribution of structural neuroimaging

G Aël Chetelat, JC Baron - Neuroimage, 2003 - Elsevier
To accurately predict the development of Alzheimer's disease (AD) at its predementia stage
would be a major breakthrough from both therapeutic and research standpoints. In this …

Presymptomatic hippocampal atrophy in Alzheimer's disease: a longitudinal MRI study

NC Fox, EK Warrington, PA Freeborough… - Brain, 1996 - academic.oup.com
The hippocampal formation (HF) is known from pathological and MRI studies to be severely
atrophied in established Alzheimer's disease. However, it is unclear when the earliest …

Relationship between hippocampal atrophy and neuropathology markers: A 7T MRI validation study of the EADC‐ADNI Harmonized Hippocampal Segmentation …

LG Apostolova, C Zarow, K Biado, S Hurtz… - Alzheimer's & …, 2015 - Wiley Online Library
Objective The pathologic validation of European Alzheimer's Disease Consortium
Alzheimer's Disease Neuroimaging Initiative Center Harmonized Hippocampal …