Protective effects of konjac glucomannan on gut microbiome with antibiotic perturbation in mice

YH Mao, Y Xu, F Song, ZM Wang, YH Li, M Zhao… - Carbohydrate …, 2022 - Elsevier
This study assessed the protective effects of konjac glucomannan (KGM) on gut microbiome
against the antibiotic perturbation in C57BL/6J mice. The native KGM (1.82× 10 7) was …

Improvement of loperamide-hydrochloride-induced intestinal motility disturbance by Platycodon grandiflorum polysaccharides through effects on gut microbes and …

M Hao, J Song, X Zhai, N Cheng, C Xu… - Frontiers in Cellular …, 2023 - frontiersin.org
Constipation is a common gastrointestinal symptom characterized by intestinal motility
disorder. The effects of Platycodon grandiflorum polysaccharides (PGP) on intestinal motility …

Konjac acts as a natural laxative by increasing stool bulk and improving colonic ecology in healthy adults

HL Chen, HC Cheng, YJ Liu, SY Liu, WT Wu - Nutrition, 2006 - Elsevier
OBJECTIVE: Konjac glucomannan (KGM) has been shown to relieve constipation, which
could be associated with increased stool bulk and improved colonic ecology. METHODS …

Effects of different oligosaccharides at various dosages on the composition of gut microbiota and short-chain fatty acids in mice with constipation

L Wang, L Hu, S Yan, T Jiang, S Fang, G Wang… - Food & Function, 2017 - pubs.rsc.org
The aim of this study was to evaluate the effects of three different kinds of oligosaccharides
(a fructo-oligosaccharide (FOS) formulation consisting of 95% FOS (FOS95); a galacto …

Effect of Durio zibethinus rind polysaccharide on functional constipation and intestinal microbiota in rats

H Jiang, J Dong, S Jiang, Q Liang, Y Zhang… - Food Research …, 2020 - Elsevier
The prevalence of constipation increases rapidly with the increased pressure of some
people's life, which seriously affects the quality of life in related patients. In this study, the …

Xiao Cheng Qi Decoction, an Ancient Chinese Herbal Mixture, Relieves Loperamide-Induced Slow-Transit Constipation in Mice: An Action Mediated by Gut Microbiota

A Tuohongerbieke, H Wang, J Wu, Z Wang, T Dong… - Pharmaceuticals, 2024 - mdpi.com
Xiao Cheng Qi (XCQ) decoction, an ancient Chinese herbal mixture, has been used in
treating slow-transit constipation (STC) for years. The underlying action mechanism in …

Modulation of gut microbiota ecosystem by a glucan-rich snail mucin heteropolysaccharide attenuates loperamide-induced constipation

H Kim, EJ Jeong, C Park, J Lee, WJ Kim, KW Yu… - International Journal of …, 2023 - Elsevier
The present study aimed to investigate the effect of oral administration of snail-derived
mucin extract (SM) on ameliorating constipation symptoms of loperamide-induced …

Cannabis sativa L. alleviates loperamide-induced constipation by modulating the composition of gut microbiota in mice

R Li, M Li, B Li, WH Chen, Z Liu - Frontiers in Pharmacology, 2022 - frontiersin.org
MaZiRenWan (MZRW) is the most frequently used Traditional Chinese Medicine formula to
treat chronic constipation, Cannabis sativa L. is regarded as a monarch drug in MZRW …

Chinese patent medicine shouhui tongbian capsule attenuated loperamide-induced constipation through modulating the gut microbiota in rat

Q Lin, M Liu, F Erhunmwunsee, B Li, Y Mou… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Shouhui tongbian capsule (SHTC) is a commercial
Chinese patent medicine used in the treatment of constipation. However, its mechanism of …

[HTML][HTML] Shouhui Tongbian Capsule ameliorates constipation via gut microbiota-5-HT-intestinal motility axis

J Bai, Y Cai, Z Huang, Y Gu, N Huang, R Sun… - Biomedicine & …, 2022 - Elsevier
Constipation has become an epidemic enteric medical problem, accompanied with
increasing long-term sequelae. Gut microbiota and serotonin (5-HT) have been believed as …