A nuclear microscopic study of elemental changes in the rat hippocampus after kainate‐induced neuronal injury

WY Ong, MQ Ren, J Makjanić, TM Lim… - Journal of …, 1999 - Wiley Online Library
The effect of intracerebroventricular kainate injection on the elemental composition of the
hippocampus was studied in adult Wistar rats, at 1 day and 1, 2, 3, and 4 weeks …

Neonatal exposure to monosodium L-glutamate induces loss of neurons and cytoarchitectural alterations in hippocampal CA1 pyramidal neurons of adult rats

C Beas-Zárate, MI Pérez-Vega, I González-Burgos - Brain Research, 2002 - Elsevier
Glutamatergic post-synaptic receptors are closely related to the known excitotoxic effects of
high doses of l-glutamate. Several behavioral abnormalities, glial reaction, and an increase …

Do kainate-lesioned hippocampi become epileptogenic?

JE Franck, PA Schwartzkroin - Brain research, 1985 - Elsevier
Kainic acid lesions of hippocampal subfields CA3–CA4 produced dramatic synchronous
afterdischarge activity in subfield CA1 when studied 2–4 weeks post-lesion in the in vitro …

Regional difference of glutamate-induced swelling in cultured rat brain astrocytes

BC Han, SB Koh, EY Lee, YH Seong - Life Sciences, 2004 - Elsevier
L-Glutamate (glutamate) is an important neurotoxin as well as the major excitatory
neurotransmitter. Extracellular glutamate levels are elevated following ischemia …

[HTML][HTML] Blockade of NMDA-receptors or calcium-channels attenuates the ischaemia-evoked efflux of glutamate and phosphoethanolamine and depression of …

F Robert, L Bert, L Stoppini - Comptes rendus biologies, 2002 - Elsevier
We have investigated the effects of various insults on extracellular glutamate and
phosphoethanolamine levels as well as electrical activity alterations in the early period …

Involvement of the different rat hippocampal glutamatergic receptors in development of seizures induced by soman: an autoradiographic study.

G Lallement, P Carpentier, I Pernot-Marino… - …, 1991 - europepmc.org
Glutamate (GLU)-receptor subtypes,(quisqualate (QA)-, kainate (KA)-, N-methyl-D-aspartate
(NMDA)-receptors) and the phencyclidine sites localized in the ion-channel associated to …

Depolarization with high-K+ causes Cal2+-independent but partially Cl−-dependent glutamate release in rat hippocampal slice cultures

M Takahashi, M Hashimoto - Neuroscience research, 1996 - Elsevier
We studied the neurotoxic glutamate release induced by high-K+ depolarization in rat
hippocampal slice cultures. Depolarization with 90 mM K+ for 30 min caused a significant …

Kainate-induced inactivation of NMDA currents via an elevation of intracellular Ca2+ in hippocampal neurons

I Medina, N Filippova, G Barbin… - Journal of …, 1994 - journals.physiology.org
1. Ionic currents and the cytosolic free calcium concentration ([Ca2+] i) were recorded in rat
hippocampal neurons in culture using the whole-cell configuration of the patch-clamp …

Reduced excitatory effect of kainic acid on rat CA3 hippocampal pyramidal neurons following destruction of the mossy projection with colchicine

C De Montigny, M Weiss, J Ouellette - Experimental brain research, 1987 - Springer
Rats were injected unilaterally with colchicine in the dentate gyrus of the dorsal
hippocampus. Two weeks later, under urethane anesthesia, extracellular recordings were …

Distribution and properties of kainate receptors distinct in the CA3 region of the hippocampus of the guinea pig

C Yamamoto, S Sawada, T Ohno-Shosaku - Brain research, 1998 - Elsevier
To characterize the nature of kainate (KA) receptors distinct in the CA3 region of the
hippocampus, properties of depolarizations induced by pulses of KA or AMPA (α-amino-3 …