Dendrimers are highly branched macromolecules of low polydispersity that provide many
exciting opportunities for design of novel drug-carriers, gene delivery systems and imaging …

About forty percent of newly developed drugs are rejected by the pharmaceutical industry
and will never benefit a patient because of poor bioavailability due to low water solubility …

Dendrimers have come a long way in the last 25 years since their inception. Originally
created as a wonder molecule of chemistry, dendrimer is now in the fourth class of polymers …

Dendrimers are versatile, derivatisable, well-defined, compartmentalised chemical polymers
with sizes and physicochemical properties resembling those of biomolecules eg proteins …

Over the past few years, utilization of dendrimers in nano-biotechnology applications such
as bio-mimicry, diagnostics, and therapeutics has attracted a great deal of attention, far …

This paper reviews the biodistribution, toxicity and pharmacokinetics of pure dendrimers and
their complexes with nucleic acids (dendriplexes) in animals, including mice, rats, rabbits …

Dendrimers are routinely synthesized as tuneable nanostructures that may be designed and
regulated as a function of their size, shape, surface chemistry and interior void space. They …

Dendrimers are prepared with a level of control not attainable with most linear polymers,
leading to nearly monodisperse, globular macromolecules with a large number of peripheral …

The synthesis, cytotoxicity, and behavior in cell culture of a new set of first‐(G1) and second‐
generation (G2) dendrimers is reported. The surface functionality of these dendrimers has …

The influence of surface modification on the cytotoxicity of PAMAM dendrimers was
examined using Caco-2 cells. Dendrimers were modified by conjugating either lauroyl …