Abstract Type 2 diabetes (T2DM) is a chronic metabolic disease characterized by insulin
resistance and impaired insulin secretion. Insulin resistance is often present in early …

Diabetes mellitus is a kind of typical metabolic disorder characterized by elevated blood
sugar levels. Atherosclerosis (AS) is one of the most common complications of diabetes …

Even before the introduction of insulin therapy in 1922, retinopathy, neuropathy and
proteinuria had all been described in association with diabetes mellitus. However, as the …

Introduction Protein molecules can universally bind non-enzymatically with glucose or other
sugars to form initially unstable aldimine and ketamine versions of the original protein and …

Publisher Summary This chapter discusses glycolysis which is a chain of linked reactions;
the conversion of glucose to ethanol and carbon dioxide or to lactic acid is energetically …

It is generally accepted that chronic hyperglycaemia is responsible for most of the long‐term
complications of diabetes. Several studies suggest that accelerated non‐enzymatic …

Glycolysis, a simple pathway of glucose metabolism, critically regulates insulin secretion
and metabolic functions of various cells. Depending on cell types, rates of glycolysis are …

Glycogen is a branched polymer of glucose that acts as a store of energy in times of
nutritional sufficiency for utilization in times of need. Its metabolism has been the subject of …

To assess the relative contributions of gluconeogenesis and glycogenolysis to overall
hepatic glucose output in postabsorptive normal humans and those of the indirect and direct …

Diabetes mellitus and glycogen storage disease type I (GSDI) may initially appear disparate
in metabolic profile: one characterized by uncontrolled hyperglycaemia due to disturbed …