Growth Phase-Dependent Variation in Protein Composition of the Escherichia coli Nucleoid

T Ali Azam, A Iwata, A Nishimura, S Ueda… - Journal of …, 1999 - Am Soc Microbiol
The genome DNA of Escherichia coli is associated with about 10 DNA-binding structural
proteins, altogether forming the nucleoid. The nucleoid proteins play some functional roles …

Two types of localization of the DNA‐binding proteins within the Escherichia coli nucleoid

TA Azam, S Hiraga, A Ishihama - Genes to Cells, 2000 - Wiley Online Library
Background The genome DNA of Escherichia coli is folded into the nucleosome‐like
structure, often called a nucleoid, by the binding of several DNA‐binding proteins. We …

Twelve species of the nucleoid-associated protein from Escherichia coli: sequence recognition specificity and DNA binding affinity

TA Azam, A Ishihama - Journal of Biological Chemistry, 1999 - ASBMB
The genome of Escherichia coli is composed of a single molecule of circular DNA with the
length of about 47,000 kilobase pairs, which is associated with about 10 major DNA-binding …

Coupling the distribution of RNA polymerase to global gene regulation and the dynamic structure of the bacterial nucleoid in Escherichia coli

DJ Jin, JE Cabrera - Journal of structural biology, 2006 - Elsevier
Prokaryotic genomes are contained in a cellular structure termed the nucleoid. However,
despite a complete genome sequence and years of intensive study of Escherichia coli, our …

Function of nucleoid-associated proteins in chromosome structuring and transcriptional regulation

CJ Dorman - Journal of molecular microbiology and biotechnology, 2015 - karger.com
Nucleoid-associated proteins typically are abundant, low-molecular-mass polypeptides that
bind DNA and alter its shape and its ability to participate in transactions such as …

Architecture of the Escherichia coli nucleoid

SC Verma, Z Qian, SL Adhya - PLoS genetics, 2019 - journals.plos.org
How genomes are organized within cells and how the 3D architecture of a genome
influences cellular functions are significant questions in biology. A bacterial genomic DNA …

Effects of nucleoid-associated proteins on bacterial chromosome structure and gene expression

DF Browning, DC Grainger, SJW Busby - Current opinion in microbiology, 2010 - Elsevier
Bacterial nucleoid-associated proteins play a key role in the organisation, replication,
segregation, repair and expression of bacterial chromosomes. Here, we review some recent …

Control of transcription by nucleoid proteins

SM McLeod, RC Johnson - Current opinion in microbiology, 2001 - Elsevier
Nucleoid proteins are a group of abundant DNA binding proteins that modulate the structure
of the bacterial chromosome. They have been recruited as specific negative and positive …

Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome

DC Grainger, D Hurd, MD Goldberg… - Nucleic acids …, 2006 - academic.oup.com
The Escherichia coli chromosome is condensed into an ill-defined structure known as the
nucleoid. Nucleoid-associated DNA-binding proteins are involved in maintaining this …

Bacterial chromatin

A Travers, G Muskhelishvili - Current opinion in genetics & development, 2005 - Elsevier
Recent studies have revealed that the bacterial nucleoid is a dynamic entity that alters its
overall structure in response to changes in both growth rate and growth phase. These …