The 72nd Annual Meeting of the Italian Society of Physiology, held in Bari in September
2022, provided a vibrant platform for the convergence of leading physiologists, fostering …

Autophagy primarily works to counteract nutrient deprivation that is strongly engaged during
starvation and hypoxia, which happens in hypoperfusion. Nonetheless, autophagy is slightly …

Traumatic brain injury (TBI) is one of the most devastating forms of brain injury. Many
pathological mechanisms such as oxidative stress, apoptosis and inflammation all contribute …

Cerebral ischemia is one of the most devastating brain injuries and a primary cause of
acquired and persistent disability worldwide. Despite ongoing therapeutic interventions at …

Stroke is one of the leading causes of death and disability worldwide. Autophagy is a
conserved cellular catabolic pathway that maintains cellular homeostasis by removal of …

Dementia is a major cause of poor quality of life, disability, and mortality in old age.
According to the geroscience paradigm, the mechanisms that drive the aging process are …

Autophagy is an important constitutive intracellular catalytic process that occurs in basal
conditions, as well as during stress in all tissues. It is induced during cellular growth, tissue …

The development of clinical stroke therapies remains elusive. The neuroprotective efficacies
of thousands of molecules and compounds have not yet been determined; however …

Autophagy is a homeostatic cellular process required for the recycling of proteins and
damaged organelles, and in most scenarios is believed to promote cell survival. However …

Stroke represents a main cause of death and permanent disability worldwide. The molecular
mechanisms underlying cerebral injury in response to the ischemic insults are not …