A randomized controlled trial of the effects of three antihypertensive agents on blood pressure control and quality of life in older women

WB Applegate, HL Phillips, H Schnaper… - Archives of Internal …, 1991 - jamanetwork.com
We conducted a multicenter, randomized, double-blind, parallel group trial to compare the
impact of titrated doses of atenolol (50 to 100 mg once a day), enalapril (5 to 20 mg once a …

Efficacy and safety of atenolol, enalapril, and isradipine in elderly hypertensive women

HM Perry Jr, WD Hall, JR Benz, DW Bartels… - The American journal of …, 1994 - Elsevier
Abstract purpose: This trial was designed to evaluate the efficacy and safety of three different
classes of antihypertensive agents in elderly women. patients and methods: The trial had …

Effects of antihypertensive medications on quality of life in elderly hypertensive women

SH Croog, MF Elias, T Colton… - American journal of …, 1994 - academic.oup.com
The impact of antihypertensive medications on the quality of life of elderly hypertensive
women has rarely been systematically evaluated in large clinical trials using drugs from the …

Influence of long-term, low-dose, diuretic-based, antihypertensive therapy on glucose, lipid, uric acid, and potassium levels in older men and women with isolated …

PJ Savage, SL Pressel, JD Curb… - Archives of Internal …, 1998 - jamanetwork.com
Background Previous studies often of short duration have raised concerns that
antihypertensive therapy with diuretics and β-blockers adversely alters levels of other …

Antihypertensive therapy and quality of life: Influence of blood pressure reduction, adverse events, and prior antihypertensive therapy

MR Weir, LM Prisant, V Papademetriou… - American journal of …, 1996 - Elsevier
Quality of life is an important attribute of antihypertensive therapy. Previous studies have not
addressed the importance of a patient's prior pharmacotherapy on quality of life, which may …

Use of antihypertensive drugs and trends in blood pressure in the elderly

RJ Glynn, DB Brock, T Harris, RJ Havlik… - Archives of internal …, 1995 - jamanetwork.com
Background: During the 1980s data became available from randomized trials concerning
the clear benefits of treating hypertension in the elderly. In three large communities, we …

Hypertension in the elderly: can we improve results of therapy?

LM Prisant, M Moser - Archives of internal medicine, 2000 - jamanetwork.com
Awareness of and therapy for hypertension in the United States have been increasing in
older patients. Despite this improvement, hypertension continues to be poorly controlled in …

Impact of the treatment of isolated systolic hypertension on behavioral variables: results from the Systolic Hypertension in the Elderly Program

WB Applegate, S Pressel, J Wittes, J Luhr… - Archives of Internal …, 1994 - jamanetwork.com
Background: Little information has been published on the impact of antihypertensive
medications on quality of life in older persons. Particular concern has existed that lowering …

Nonpharmacologic intervention to reduce blood pressure in older patients with mild hypertension

WB Applegate, ST Miller, JT Elam… - Archives of Internal …, 1992 - jamanetwork.com
Background.—Although nonpharmacologic interventions are widely recommended in the
therapy of high blood pressure in older adults, surprisingly little data exist to confirm the …

Hypertension in elderly patients

WB Applegate - Annals of internal medicine, 1989 - acpjournals.org
Purpose: To synthesize and analyze new information on the epidemiology, pathophysiology,
and management of hypertension in the elderly to guide physicians making treatment …