Astrocyte (As) bidirectional dialog with neurons plays a fundamental role in major
homeostatic brain functions, particularly providing metabolic support and antioxidant self …

During aging—one the most potent risk factors for Parkinson's disease (PD)—both
astrocytes and microglia undergo functional changes that ultimately hamper homoeostasis …

Oxidative stress and inflammation have long been recognized to contribute to Parkinson's
disease (PD), a common movement disorder characterized by the selective loss of midbrain …

Wnt/β-catenin signaling is required for specification and neurogenesis of midbrain
dopaminergic (mDA) neurons, the pivotal neuronal population that degenerates in …

A common hallmark of age‐dependent neurodegenerative diseases is an impairment of
adult neurogenesis. Wingless‐type mouse mammary tumor virus integration site (Wnt)/β …

Aging and exposure to environmental toxins including MPTP (1-methyl-4-phenyl-1, 2, 3, 6-
tetrahydropyridine) are strong risk factors for developing Parkinson's disease (PD), a …

Neuroinflammatory processes are recognized key contributory factors in Parkinson's
disease (PD) physiopathology. While the causes responsible for the progressive loss of …

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by
progressive loss of dopaminergic (DA ergic) neuronal cell bodies in the substantia nigra …

During the past three decades, the Wingless-type MMTV integration site (Wnt) signaling
cascade has emerged as an essential system regulating multiple processes in developing …

Parkinsons' disease (PD), a common neurodegenerative disorder, is characterized by
progressive loss of dopaminergic (DAergic) neurons in the subtantia nigra pars compacta …