Efficacy and safety of transdermal fentanyl and sustained-release oral morphine in patients with cancer and chronic non-cancer pain

AJ Clark, SH Ahmedzai, LG Allan… - … medical research and …, 2004 - Taylor & Francis
Purpose: To evaluate effectiveness and safety information of transdermal fentanyl
(TDF)(Duragesic/Durogesic*) and sustained-release oral morphine (SRM) in cancer pain …

Use of transdermal fentanyl without prior opioid stabilization in patients with cancer pain

MO Tawfik, V Bryuzgin, G Kourteva… - … medical research and …, 2004 - Taylor & Francis
Objective: To determine the safety and efficacy of transdermal fentanyl for pain relief in
cancer patients and to compare the effects on patients according to whether they had …

Transdermal fentanyl as a front-line approach to moderate-severe pain: a meta-analysis of randomized clinical trials

D Tassinari, S Sartori, E Tamburini… - … of palliative care, 2009 - journals.sagepub.com
Objective: The safety of transdermal fentanyl (TF) in comparison with slow-release oral
morphine (SROM) in moderate-severe pain was assessed. Design: A systematic review of …

[HTML][HTML] Transdermal fentanyl versussustained-release oral morphine in cancer pain: Preference, efficacy, and quality of life

S Ahmedzai, D Brooks… - Journal of pain and …, 1997 - Elsevier
Cancer patients requiring strong opioid analgesia (n= 202; mean age, 61.5 years; range, 18–
89 years; 55% men) were recruited from 38 United Kingdom palliative care centers into a …

Transdermal fentanyl: an updated review of its pharmacological properties and therapeutic efficacy in chronic cancer pain control

RBR Muijsers, AJ Wagstaff - Drugs, 2001 - Springer
Fentanyl is a synthetic opioid agonist which interacts primarily with the μ-opioid receptor.
The low molecular weight, high potency and lipid solubility of fentanyl make it suitable for …

Long‐term cancer pain management in morphine pre‐treated and opioid naive patients with transdermal fentanyl

K Mystakidou, E Tsilika, E Parpa… - … journal of cancer, 2003 - Wiley Online Library
There is emerging data supporting the use of TTS‐F (transdermal therapeutic system‐
fentanyl) in opioid naive patients. Our study examines the safety and efficacy of TTS‐F in the …

Comparison of TTS-fentanyl with sustained-release oral morphine in the treatment of patients not using opioids for mild-to-moderate pain

R Van Seventer, JM Smit, RM Schipper… - … medical research and …, 2003 - Taylor & Francis
Objective: This randomised, multicentre, direct open comparative trial evaluated the efficacy,
treatment convenience, tolerability and safety aspects of transdermal therapeutic system …

Efficacy and adverse effects of transdermal fentanyl and sustained-release oral morphine in treating moderate-severe cancer pain in Chinese population: a systematic …

Q Yang, DR Xie, ZM Jiang, W Ma, YD Zhang… - Journal of Experimental …, 2010 - Springer
Background Previous meta-analysis suggested that transdermal fentanyl was not inferior to
sustained-release oral morphine in treating moderate-severe cancer pain with less adverse …

[HTML][HTML] Transdermal fentanyl in opioid-naive cancer pain patients: an open trial using transdermal fentanyl for the treatment of chronic cancer pain in opioid-naive …

APE Vielvoye-Kerkmeer, C Mattern… - Journal of pain and …, 2000 - Elsevier
To treat cancer pain, physicians often decide to jump directly from step 1 of the World Health
Organization (WHO) analgesic ladder to step 3. The use of transdermal fentanyl in patients …

Transdermal fentanyl in the management of cancer pain in ambulatory patients: an open-label pilot study

JE Hammack, JA Mailliard, CL Loprinzi… - Journal of pain and …, 1996 - Elsevier
We performed an open-label pilot study to define analgesic efficacy, acceptability, and
toxicity of transdermal fentanyl in an ambulatory population of patients with cancer pain. Our …