PURPOSE: To quantitatively evaluate hyperpolarized helium 3 (3He) diffusion magnetic
resonance (MR) images of the lung in patients with emphysema and to determine whether …

Purpose To measure the apparent diffusion coefficient (ADC) of hyperpolarized (HP) 3He
gas using diffusion weighted MRI in healthy volunteers and patients with emphysema and …

Diffusion MRI of hyperpolarized 3He shows that the apparent diffusion coefficient (ADC) of
3He gas is highly restricted in the normal lung and becomes nearly unrestricted in severe …

Purpose To determine the reproducibility of several parameters of the ADC measurement by
calculating the scan‐to‐scan intrasubject variability. Materials and Methods Measurements …

The apparent diffusion coefficients (ADCs) of hyperpolarized 3He and 129Xe gases were
measured in the lungs of rabbits with elastase-induced emphysema and correlated against …

Purpose: To prospectively compare apparent diffusion coefficient (ADC) measurements
derived from diffusion-weighted hyperpolarized helium 3 (3He) magnetic resonance (MR) …

INTRODUCTION:: This study aims to quantify global and regional changes of diffusive
motion of 3He gas within the lung, as determined by hyperpolarized 3He MR apparent …

Hyperpolarised gases have been most recently used in magnetic resonance imaging to
demonstrate new image-derived pulmonary function parameters. One of these parameters is …

Purpose To determine whether hyperpolarized helium‐3 (HHe) diffusion MR can detect the
expected enlargement of alveoli that occurs with lung growth during childhood. Materials …

RATIONALE AND OBJECTIVES: Emphysema and small airway obstruction are the
pathological hallmarks of chronic obstructive pulmonary disease (COPD). The aim of this …