Objective: To review the rationale, clinical practice guideline recommendations, and clinical
trial data describing bleeding and clinical outcomes associated with the use of the …

Basierend auf einer Vielzahl randomisierter Studien sind Thrombozytenfunktionshemmer
zum festen Bestandteil der medikamentösen Sekundärprophylaxe atherothrombotischer …

Antiplatelet therapy is the current criterion standard for the treatment of patients undergoing
percutaneous coronary intervention and patients who have acute coronary syndromes …

This is a comment on" Cost effectiveness of aspirin, clopidogrel, or both for secondary
prevention of coronary heart disease." N Engl J Med. 2002 Jun 6; 346 (23): 1800-6. This is a …

Given the rapid evolution of cardiovascular medicine, clinicians must sift through an
enormous array of information about new therapies in order to determine how best to treat …

The design of the HOST-EXAM trial was inspired by two main considerations:(i) 25 years
ago, the CAPRIE trial reported an apparent benefit of clopidogrel vs. medium-dose aspirin …

Background—We studied the benefits and risks of adding clopidogrel to different doses of
aspirin in the treatment of patients with acute coronary syndrome (ACS). Methods and …

Background—Little is known about how clinicians use platelet function testing to guide
choice and dosing of adenosine diphosphate receptor inhibitor (ADPri) therapy in routine …

Long-term use of low-dose aspirin monotherapy is a Class I guideline-recommended
treatment in patients with prior myocardial infarction (MI), stroke, or coronary …

Background Repeat hospitalizations of patients with atherosclerosis represent a
considerable burden on the health care system. We sought to determine whether …