Biomarker predictors for immunotherapy benefit in breast: beyond PD-L1

JL James, JM Balko - Current breast cancer reports, 2019 - Springer
Abstract Purpose of Review Immune checkpoint blockade (ICB) has changed the clinical
course of multiple cancer types and durable responses have now been observed in breast …

Understanding resistance to immune checkpoint inhibitors in advanced breast cancer

P Tarantino, R Barroso-Sousa… - Expert Review of …, 2022 - Taylor & Francis
Introduction The addition of immune checkpoint inhibitors (ICIs) to frontline chemotherapy
has improved survival for patients with advanced triple-negative breast cancer (TNBC) …

A review of immune checkpoint blockade in breast cancer

B Pellegrino, C Tommasi, OE Cursio, A Musolino… - Seminars in …, 2021 - Elsevier
In the recent years characterized by the cancer immunotherapy revolution, attention has
turned to how to potentially boost and/or generate an efficient anti-tumor immune response …

Biomarkers of immune checkpoint blockade response in triple-negative breast cancer

J Isaacs, C Anders, H McArthur, J Force - Current treatment options in …, 2021 - Springer
Opinion statement Immune checkpoint blockade (ICB) has revolutionized the treatment
landscape across multiple solid tumor types. In triple-negative breast cancer (TNBC), clinical …

Biomarkers for breast cancer immunotherapy: PD-L1, TILs, and beyond

A Rizzo, AD Ricci - Expert opinion on investigational drugs, 2022 - Taylor & Francis
ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) have recently entered into the
therapeutic scenario of metastatic breast cancer. However, only a proportion of patients …

Current treatment and future trends of immunotherapy in breast cancer

MJ Elliott, B Wilson, DW Cescon - Current Cancer Drug Targets, 2022 - ingentaconnect.com
Immunotherapy continues to redefine the solid tumor treatment landscape, with inhibitors of
the PD-L1/PD-1 immune checkpoint having the most widespread impact. As the most …

Biomarkers of immunotherapy response in breast cancer beyond PD-L1

N Chic, F Brasó-Maristany, A Prat - Breast Cancer Research and …, 2022 - Springer
Immune checkpoint inhibitors have modified the treatment algorithm in a variety of cancer
types, including breast cancer. Nevertheless, optimal selection of ideal candidates to these …

The anti-cancer immune response in breast cancer: current and emerging biomarkers and treatments

VC Rayson, MA Harris, P Savas, ML Hun, B Virassamy… - Trends in Cancer, 2024 - cell.com
Triple-negative breast cancers (TNBCs) exhibit heightened T cell infiltration, contributing to
an enhanced response to immune checkpoint blockade (ICB) compared with other …

Immunotherapy in breast cancer patients: A focus on the use of the currently available biomarkers in oncology

C Criscitiello, E Guerini-Rocco, G Viale… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Immune Checkpoint Inhibitors (ICIs) have remarkably modified the way solid tumors are
managed, including breast cancer. Unfortunately, only a relatively small number of breast …

Role of immunotherapy in breast cancer

SL Jacob, LA Huppert, HS Rugo - JCO Oncology Practice, 2023 - ascopubs.org
The advent of immunotherapy, particularly immune checkpoint inhibitors (ICIs), has
revolutionized the treatment of solid tumor malignancies. In breast cancer, the most robust …