The critical role of myostatin in differentiation of sheep myoblasts
C Liu, W Li, X Zhang, N Zhang, S He, J Huang… - Biochemical and …, 2012 - Elsevier
Myostatin [MSTN, also known as growth differentiation factor 8 (GDF8)], is an inhibitor of
skeletal muscle growth. Blockade of MSTN function has been reported to result in increased …
skeletal muscle growth. Blockade of MSTN function has been reported to result in increased …
Knockdown of endogenous myostatin promotes sheep myoblast proliferation
C Liu, W Li, X Zhang, N Zhang, S He, J Huang… - In Vitro Cellular & …, 2014 - Springer
Myostatin (MSTN), is a known negative regulator of myogenesis. Silencing of the function of
MSTN could result in increasing muscle mass in mice. To determine the function of …
MSTN could result in increasing muscle mass in mice. To determine the function of …
Short-hairpin mediated myostatin knockdown resulted in altered expression of myogenic regulatory factors with enhanced myoblast proliferation in fetal myoblast cells …
Myostatin (MSTN) is a well-known negative regulator of skeletal muscle development.
Reduced expression due to natural mutations in the coding region and knockout as well as …
Reduced expression due to natural mutations in the coding region and knockout as well as …
Myostatin knockdown and its effect on myogenic gene expression program in stably transfected goat myoblasts
AK Patel, AK Tripathi, UA Patel, RK Shah… - In Vitro Cellular & …, 2014 - Springer
Myostatin, a negative regulator of skeletal muscle mass, is a proven candidate to modulate
skeletal muscle mass through targeted gene knockdown approach. Here, we report …
skeletal muscle mass through targeted gene knockdown approach. Here, we report …
Small interfering RNA (siRNA)-mediated knockdown of myostatin influences the expression of myogenic regulatory factors in caprine foetal myoblasts
Myostatin (MSTN) acts as a negative regulator of skeletal muscle development. Naturally
occurring inactivating mutations in the coding region and knockout as well as knockdown of …
occurring inactivating mutations in the coding region and knockout as well as knockdown of …
A novel mechanism of myostatin regulation by its alternative splicing variant during myogenesis in avian species
Myostatin (MSTN) is a key negative regulator of muscle growth and development, and an
increase of muscle mass is achieved by inhibiting MSTN signaling. In the current study, five …
increase of muscle mass is achieved by inhibiting MSTN signaling. In the current study, five …
Knockdown of myostatin expression by RNAi enhances muscle growth in transgenic sheep
S Hu, W Ni, W Sai, H Zi, J Qiao, P Wang, J Sheng… - PloS one, 2013 - journals.plos.org
Myostatin (MSTN) has been shown to be a negative regulator of skeletal muscle
development and growth. MSTN dysfunction therefore offers a strategy for promoting animal …
development and growth. MSTN dysfunction therefore offers a strategy for promoting animal …
Exogenous expression of an alternative splicing variant of myostatin prompts leg muscle fiber hyperplasia in Japanese quail
PR Chen, Y Suh, S Shin, RM Woodfint… - International journal of …, 2019 - mdpi.com
Myostatin (MSTN) negatively regulates muscle growth and development through inhibiting
myoblast proliferation and differentiation. Five alternative splicing isoforms of MSTN (MSTN …
myoblast proliferation and differentiation. Five alternative splicing isoforms of MSTN (MSTN …
Myostatin gene promoter: structure, conservation and importance as a target for muscle modulation
CVC Grade, CS Mantovani, LE Alvares - Journal of animal science and …, 2019 - Springer
Myostatin (MSTN) is one of the key factors regulating myogenesis. Because of its role as a
negative regulator of muscle mass deposition, much interest has been given to its protein …
negative regulator of muscle mass deposition, much interest has been given to its protein …
[PDF][PDF] Review of myostatin history, physiology and applications
H Arnold, MA Della-Fera, CA Baile - Int. Arch. Biosci, 2001 - paulogentil.com
Myostatin, a negative regulator of muscle cell growth, is highly conserved across species.
The loss of functional Myostatin is known to cause the “double-muscled” phenotype in …
The loss of functional Myostatin is known to cause the “double-muscled” phenotype in …