Cirrhosis is a form of liver fibrosis resulting from chronic hepatitis and caused by various liver
diseases, including viral hepatitis, alcoholic liver damage, nonalcoholic steatohepatitis, and …

Activation of hepatic stellate cells (HSCs) is a pivotal cellular event in liver fibrosis.
Therefore, improving our understanding of the molecular pathways that are involved in these …

Liver fibrosis is a life-threatening disease, with challenging morbidity and mortality for
healthcare systems worldwide. It imparts an enormous economic burden to societies …

Chronic hepatitis C virus (HCV) infection is one of the major causes of serious liver
diseases, including liver cirrhosis. There are no anti-fibrotic drugs with efficacy against liver …

Abstract β‑catenin, a core component of Wnt/β‑catenin signaling, has been shown to be an
important regulator of cellular proliferation and differentiation. Abnormal activation of Wnt/β …

Wnt/β-catenin is involved in every aspect of embryonic development and in the
pathogenesis of many human diseases, and is also implicated in organ fibrosis. However …

Wnt/β‐catenin signaling is emerging as a forerunner for its critical roles in many facets of
human biology. Its roles in embryogenesis, organogenesis, and maintaining tissue and …

The liver is an organ that performs a multitude of functions, and its health is pertinent and
indispensable to survival. Thus, the cellular and molecular machinery driving hepatic …

The Wnt signaling pathway is an evolutionarily conserved, highly complex signaling
pathway that is critical for development, differentiation and cellular homeostasis. The protein …

Liver cancer is among the leading global healthcare issues associated with high morbidity
and mortality. Liver cancer consists of hepatocellular carcinoma (HCC), cholangiocarcinoma …