Identification of Arx transcriptional targets in the developing basal forebrain
CT Fulp, G Cho, ED Marsh, IM Nasrallah… - Human molecular …, 2008 - academic.oup.com
Mutations in the aristaless-related homeobox (ARX) gene are associated with multiple
neurologic disorders in humans. Studies in mice indicate Arx plays a role in neuronal …
neurologic disorders in humans. Studies in mice indicate Arx plays a role in neuronal …
Conditional Loss of Arx From the Developing Dorsal Telencephalon Results in Behavioral Phenotypes Resembling Mild Human ARX Mutations
JC Simonet, CN Sunnen, J Wu, JA Golden… - Cerebral …, 2015 - academic.oup.com
Abstract Mutations in the Aristaless-Related Homeobox (ARX) gene cause structural
anomalies of the brain, epilepsy, and neurocognitive deficits in children. During forebrain …
anomalies of the brain, epilepsy, and neurocognitive deficits in children. During forebrain …
Targeted loss of Arx results in a developmental epilepsy mouse model and recapitulates the human phenotype in heterozygous females
Mutations in the X-linked aristaless-related homeobox gene (ARX) have been linked to
structural brain anomalies as well as multiple neurocognitive deficits. The generation of Arx …
structural brain anomalies as well as multiple neurocognitive deficits. The generation of Arx …
High-Throughput Analysis of Promoter Occupancy Reveals New Targets for Arx, a Gene Mutated in Mental Retardation and Interneuronopathies
ML Quille, S Carat, S Quéméner-Redon, E Hirchaud… - PloS one, 2011 - journals.plos.org
Genetic investigations of X-linked intellectual disabilities have implicated the ARX
(Aristaless-related homeobox) gene in a wide spectrum of disorders extending from …
(Aristaless-related homeobox) gene in a wide spectrum of disorders extending from …
Developmental interneuron subtype deficits after targeted loss of Arx
ED Marsh, MLP Nasrallah, C Walsh, KA Murray… - BMC neuroscience, 2016 - Springer
Background Aristaless-related homeobox (ARX) is a paired-like homeodomain transcription
factor that functions primarily as a transcriptional repressor and has been implicated in …
factor that functions primarily as a transcriptional repressor and has been implicated in …
Cell-autonomous roles of ARX in cell proliferation and neuronal migration during corticogenesis
G Friocourt, S Kanatani, H Tabata, M Yozu… - Journal of …, 2008 - Soc Neuroscience
The aristaless-related homeobox (ARX) gene has been implicated in a wide spectrum of
disorders ranging from phenotypes with severe neuronal migration defects, such as …
disorders ranging from phenotypes with severe neuronal migration defects, such as …
ARX Regulates Cortical Intermediate Progenitor Cell Expansion and Upper Layer Neuron Formation Through Repression of Cdkn1c
G Colasante, JC Simonet, R Calogero, S Crispi… - Cerebral …, 2015 - academic.oup.com
Mutations in the Aristaless-related homeobox (ARX) gene are found in a spectrum of
epilepsy and X-linked intellectual disability disorders. During development Arx is expressed …
epilepsy and X-linked intellectual disability disorders. During development Arx is expressed …
Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice
K Kitamura, Y Itou, M Yanazawa… - Human molecular …, 2009 - academic.oup.com
ARX (the aristaless-related homeobox gene) is a transcription factor that participates in the
development of GABAergic and cholinergic neurons in the forebrain. Many ARX mutations …
development of GABAergic and cholinergic neurons in the forebrain. Many ARX mutations …
[HTML][HTML] Identification of Arx targets unveils new candidates for controlling cortical interneuron migration and differentiation
G Friocourt, JG Parnavelas - Frontiers in cellular neuroscience, 2011 - frontiersin.org
Mutations in the homeobox transcription factor ARX have been found to be responsible for a
wide spectrum of disorders extending from phenotypes with severe neuronal migration …
wide spectrum of disorders extending from phenotypes with severe neuronal migration …
The phenotypic spectrum of ARX mutations
M Suri - Developmental medicine and child neurology, 2005 - cambridge.org
In 1997, Miura et al. isolated a novel homeobox gene in zebrafish and mice with striking
homology to the Drosophila gene aristaless. They called this gene Arx (aristaless-related …
homology to the Drosophila gene aristaless. They called this gene Arx (aristaless-related …