CSF-1 receptor signaling in myeloid cells
ER Stanley, V Chitu - Cold Spring Harbor perspectives …, 2014 - cshperspectives.cshlp.org
The CSF-1 receptor (CSF-1R) is activated by the homodimeric growth factors colony-
stimulating factor-1 (CSF-1) and interleukin-34 (IL-34). It plays important roles in …
stimulating factor-1 (CSF-1) and interleukin-34 (IL-34). It plays important roles in …
Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells
S Wei, S Nandi, V Chitu, YG Yeung… - Journal of leukocyte …, 2010 - academic.oup.com
CSF-1 and the novel CSF-1 receptor ligand, IL-34, possess similar CSF-1R-mediated
activities, but differ in their spatio-temporal expression, permitting complementary CSF-1 …
activities, but differ in their spatio-temporal expression, permitting complementary CSF-1 …
Function of CSF1 and IL34 in macrophage homeostasis, inflammation, and cancer
WY Lin, D Xu, CD Austin, P Caplazi, K Senger… - Frontiers in …, 2019 - frontiersin.org
Colony-stimulating factor 1 (CSF1) and interleukin 34 (IL34) signal via the CSF1 receptor to
regulate macrophage differentiation. Studies in IL34-or CSF1-deficient mice have revealed …
regulate macrophage differentiation. Studies in IL34-or CSF1-deficient mice have revealed …
The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1
H Liu, C Leo, X Chen, BR Wong, LT Williams… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Interleukin-34 (IL-34) and colony stimulating factor-1 (CSF-1) both signal through the CSF-
1R receptor tyrosine kinase, but they have no sequence homology, and their functions and …
1R receptor tyrosine kinase, but they have no sequence homology, and their functions and …
IL-34 and CSF-1, deciphering similarities and differences at steady state and in diseases
A Freuchet, A Salama, S Remy… - Journal of Leukocyte …, 2021 - academic.oup.com
Abstract Although IL-34 and CSF-1 share actions as key mediators of monocytes/
macrophages survival and differentiation, they also display differences that should be …
macrophages survival and differentiation, they also display differences that should be …
IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation
T Chihara, S Suzu, R Hassan… - Cell Death & …, 2010 - nature.com
Macrophage colony-stimulating factor (M-CSF) regulates the production, survival and
function of macrophages through Fms, the receptor tyrosine kinase. Recently, interleukin-34 …
function of macrophages through Fms, the receptor tyrosine kinase. Recently, interleukin-34 …
[HTML][HTML] The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and …
S Nandi, S Gokhan, XM Dai, S Wei, G Enikolopov… - Developmental …, 2012 - Elsevier
The CSF-1 receptor (CSF-1R) regulates CNS microglial development. However, the
localization and developmental roles of this receptor and its ligands, IL-34 and CSF-1, in the …
localization and developmental roles of this receptor and its ligands, IL-34 and CSF-1, in the …
Pivotal Advance: Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products
These studies demonstrate that CSF-1 and IL-34 are conserved in birds, and uses
evolutionary comparisons to infer structure function relationships among vertebrate animals …
evolutionary comparisons to infer structure function relationships among vertebrate animals …
IL-34 and CSF-1: similarities and differences
Y Nakamichi, N Udagawa, N Takahashi - Journal of bone and mineral …, 2013 - Springer
Abstract Colony-stimulating factor-1 (CSF-1) is widely expressed and considered to regulate
the development, maintenance, and function of mononuclear phagocyte lineage cells such …
the development, maintenance, and function of mononuclear phagocyte lineage cells such …
Emerging roles of IL-34 in health and disease
I Lelios, D Cansever, SG Utz, W Mildenberger… - Journal of Experimental …, 2020 - rupress.org
Macrophages are part of the innate immune system and are present in every organ of the
body. They fulfill critical roles in tissue homeostasis and development and are involved in …
body. They fulfill critical roles in tissue homeostasis and development and are involved in …