The intrinsic properties of therapeutic proteins generally present a major impediment for
transdermal delivery, including their relatively large molecule size and susceptibility to …

The growing demand for patient-compliance therapies in recent years has led to the
development of transdermal drug delivery, which possesses several advantages compared …

The success of protein, peptide and antibody based therapies is evident-the
biopharmaceuticals market is predicted to reach $388 billion by 2024 [1], and more than half …

Polymeric microneedle (MN) systems are interesting transdermal drug delivery systems
because of their controlled drug delivery, tunable properties, and ease of patient self …

Many promising therapeutic agents are limited by their inability to reach the systemic
circulation, due to the excellent barrier properties of biological membranes, such as the …

Human skin is a multilayered physiochemical barrier protecting the human body. The
stratum corneum (SC) is the outermost keratinized layer of skin through which only …

Transdermal drug delivery is contemplated as one of the top appealing routes for
pharmaceutically active ingredients administration owing to the several benefits, specifically …

Proteins and peptides have become a significant therapeutic modality for various diseases
because of their high potency and specificity. However, the inherent properties of these …

Transdermal drug delivery using microneedles is increasingly gaining interest due to the
issues associated with oral drug delivery routes. Gastrointestinal route exposes the drug to …

In recent years, transdermal drug delivery based on microneedles (MNs) technology has
received extensive attention, which offers a safer and painless alternative to hypodermic …