[HTML][HTML] Identification of Glycyrrhiza as the rikkunshito constituent with the highest antagonistic potential on heterologously expressed 5-HT3A receptors due to the …
R Herbrechter, PM Ziemba, KM Hoffmann… - Frontiers in …, 2015 - frontiersin.org
The traditional Japanese phytomedicine rikkunshito is traditionally used for the treatment of
gastrointestinal motility disorders, cachexia and nausea. These effects indicate 5-HT3 …
gastrointestinal motility disorders, cachexia and nausea. These effects indicate 5-HT3 …
[HTML][HTML] Hydroxy pentacyclic triterpene acid, kaempferol, inhibits the human 5-hydroxytryptamine type 3A receptor activity
S Lee, HS Seol, S Eom, J Lee, C Kim, JH Park… - International Journal of …, 2022 - mdpi.com
Monoamine serotonin is a major neurotransmitter that acts on a wide range of central
nervous system and peripheral nervous system functions and is known to have a role in …
nervous system and peripheral nervous system functions and is known to have a role in …
Structure–Activity Relationships of Quinoxaline‐Based 5‐HT3A and 5‐HT3AB Receptor‐Selective Ligands
AJ Thompson, MHP Verheij… - …, 2013 - Wiley Online Library
Until recently, discriminating between homomeric 5‐HT3A and heteromeric 5‐HT3AB
receptors was only possible with ligands that bind in the receptor pore. This study describes …
receptors was only possible with ligands that bind in the receptor pore. This study describes …
[HTML][HTML] The Traditional Japanese Medicine Rikkunshito Promotes Gastric Emptying via the Antagonistic Action of the 5-HT3 Receptor Pathway in Rats
K Tominaga, T Kido, M Ochi, C Sadakane… - Evidence-Based …, 2011 - hindawi.com
The traditional Japanese medicine rikkunshito ameliorates the nitric oxide-associated delay
in gastric emptying. Whether rikkunshito affects gastric motility associated with 5 …
in gastric emptying. Whether rikkunshito affects gastric motility associated with 5 …
5‐Hydroxytryptamine2A receptor binding activity of compounds from Litsea sessilis
LY Chung, MW Lo, MR Mustafa… - … Journal Devoted to …, 2009 - Wiley Online Library
A 96‐well microplate filtration based 5‐HT2A receptor‐radioligand binding assay was
optimized and adopted to carry out a bioassay‐guided fractionation of the methanol extract …
optimized and adopted to carry out a bioassay‐guided fractionation of the methanol extract …
Inhibition of [3H]-LSD Binding to 5-HT7 Receptors by Flavonoids from Scutellaria lateriflora
S Gafner, C Bergeron, LL Batcha, J Reich… - Journal of Natural …, 2003 - ACS Publications
The hot water and 70% ethanol extracts of dried mad-dog skullcap (Scutellaria lateriflora)
both bound to the 5-HT7 receptor, with 87.2±6.2% and 56.7±1.3% inhibition of [3H]-LSD …
both bound to the 5-HT7 receptor, with 87.2±6.2% and 56.7±1.3% inhibition of [3H]-LSD …
Mode of action of gingerols and shogaols on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum
H Abdel-Aziz, T Windeck, M Ploch… - European journal of …, 2006 - Elsevier
Ginger (rhizomes of Zingiber officinale) has been shown to exert potent anti-emetic
properties, but its mode of action has not yet been elucidated. Among its active …
properties, but its mode of action has not yet been elucidated. Among its active …
Partial agonistic effect of yokukansan on human recombinant serotonin 1A receptors expressed in the membranes of Chinese hamster ovary cells
K Terawaki, Y Ikarashi, K Sekiguchi, Y Nakai… - Journal of …, 2010 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Yokukansan (YKS) is a traditional Japanese
medicine consisted of seven medicinal herbs and has been used for treatment of neurosis …
medicine consisted of seven medicinal herbs and has been used for treatment of neurosis …
5-HT7 receptor modulators: Amino groups attached to biphenyl scaffold determine functional activity
HT 7 receptor (5-HT 7 R) agonists and antagonists have been reported to be used for
treatment of neuropathic pain and depression, respectively. In this study, as a novel scaffold …
treatment of neuropathic pain and depression, respectively. In this study, as a novel scaffold …
5-HT3 receptor blocking activity of arylalkanes isolated from the rhizome of Zingiber officinale
H Abdel-Aziz, A Nahrstedt, F Petereit, T Windeck… - Planta …, 2005 - thieme-connect.com
Different extracts (ethanolic, hexane, aqueous) of ginger (rhizomes of Zingiber officinale)
and the essential oil were tested using [14 C] guanidinium influx into N1E-115 cells and the …
and the essential oil were tested using [14 C] guanidinium influx into N1E-115 cells and the …