Objectives: Nausea and vomiting are the most frequently reported side-effects by patients
who are given general anesthesia perioperatively and patients with cancer who undergo …

In this work we examined the affinity and the selectivity of V. adscendens, Iresine herbstii
Hook.(Amaranthaceae) and Brugmansia arborea (L.) Lagerheim (Solanaceae) towards 5 …

MATERIALS AND METHODS Plant Materials The root of C. sinica was collected at
Changnyeong-gun, Gyeongsangnam-do, Korea in July 1995 and the plant was identified by …

Background We recently focused on alkaloids in Uncaria hook (a constituent of the Kampo
medicine, yokukansan) and identified the pharmacological action of geissoschizine methyl …

Kampo medicine is a form of Japanese phytotherapy originating from traditional Chinese
medicine (TCM). During the last several decades, much attention has been paid to the …

Background Beneficial effects of ginger in the treatment of gastrointestinal (GI) problems and
chemotherapy‐induced nausea and vomiting are well accepted. In rodents, the action of …

To investigate the antiemetic effect of the active extract (ginger ether extract, GEE) and its
bioactive compounds in ginger, the pica vomiting model in rats and the gastric emptying …

Based on our earlier studies of structure activity relationships on 4-substituted piperazine
derivatives, in this work we synthesized a novel set of long-chain arylpiperazines with the …

The serotonin receptor 5-HT1B is widely expressed in the central nervous system and has
been considered a drug target in a variety of cognitive and psychiatric disorders. The anti …

Nausea and emesis are a major side effect and obstacle for chemotherapy in cancer
patients. Employ of antiemetic drugs help to suppress chemotherapy− induced emesis in …