Bacteriophage procurement for therapeutic purposes

B Weber-Dąbrowska, E Jończyk-Matysiak… - Frontiers in …, 2016 - frontiersin.org
Bacteriophages (phages), discovered 100 years ago, are able to infect and destroy only
bacterial cells. In the current crisis of antibiotic efficacy, phage therapy is considered as a …

Revisiting phage therapy: new applications for old resources

FL Nobrega, AR Costa, LD Kluskens, J Azeredo - Trends in microbiology, 2015 - cell.com
The success of phage therapy is dependent on the development of strategies able to
overcome the limitations of bacteriophages as therapeutic agents, the creation of an …

Approaches to optimize therapeutic bacteriophage and bacteriophage-derived products to combat bacterial infections

M Reuter, DH Kruger - Virus Genes, 2020 - Springer
The emerging occurrence of antibiotic-resistant bacterial pathogens leads to a recollection
of bacteriophage as antimicrobial therapeutics. This article presents a short overview of the …

[HTML][HTML] The resurgence of phage-based therapy in the era of increasing antibiotic resistance: from research progress to challenges and prospects

NJ Anyaegbunam, CC Anekpo… - Microbiological …, 2022 - Elsevier
Phage therapy was implemented almost a century ago but was subsequently abandoned
when antibiotics emerged. However, the rapid emergence of drug-resistant, which has …

Genetic engineering of bacteriophages against infectious diseases

Y Chen, H Batra, J Dong, C Chen, VB Rao… - Frontiers in …, 2019 - frontiersin.org
Bacteriophages (phages) are the most abundant and widely distributed organisms on Earth,
constituting a virtually unlimited resource to explore the development of biomedical …

Designing phage therapeutics

LD Goodridge - Current pharmaceutical biotechnology, 2010 - ingentaconnect.com
Phage therapy is the application of phages to bodies, substances, or environments to effect
the biocontrol of pathogenic or nuisance bacteria. To be effective, phages, minimally, must …

The many applications of engineered bacteriophages—An overview

B Gibb, P Hyman, CL Schneider - Pharmaceuticals, 2021 - mdpi.com
Since their independent discovery by Frederick Twort in 1915 and Felix d'Herelle in 1917,
bacteriophages have captured the attention of scientists for more than a century. They are …

[HTML][HTML] Bacteriophage therapy: recent developments and applications of a renaissant weapon

B Fathima, AC Archer - Research in microbiology, 2021 - Elsevier
Antimicrobial resistance is a global health problem and one of the leading concerns in
healthcare sector. Bacteriophages are antibacterial agents ubiquitous in nature. With …

[HTML][HTML] Phage therapy: From biological mechanisms to future directions

SA Strathdee, GF Hatfull, VK Mutalik, RT Schooley - Cell, 2023 - cell.com
Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research,
the natural predators of bacteria discovered over 100 years ago. In order to use phages …

Back to the future: bacteriophages as promising therapeutic tools

P Domingo‐Calap, P Georgel, S Bahram - Hla, 2016 - Wiley Online Library
Bacteriophages (phages), natural predators of bacteria, are becoming increasingly attractive
in medical and pharmaceutical applications. After their discovery almost a century ago, they …