A functional m6A‐RNA methylation pathway in the oyster Crassostrea gigas assumes epitranscriptomic regulation of lophotrochozoan development

L Le Franc, B Bernay, B Petton, M Since… - The FEBS …, 2021 - Wiley Online Library
N6‐methyladenosine (m6A) is a prevalent epitranscriptomic mark in eukaryotic RNA, with
crucial roles for mammalian and ecdysozoan development. Indeed, m6A‐RNA and the …

Global N6-methyladenosine methylation analysis reveals the positive correlation between m6A modification and mRNA abundance during Apostichopus japonicus …

Y Shao, X Duan, X Zhao, Z Lv, C Li - Developmental & Comparative …, 2022 - Elsevier
Abstract N 6-methyladenosine (m 6 A), the most abundant epitranscriptomic modification in
eukaryotic messenger RNA (mRNA), plays important roles in regulation of gene expression …

m6A modulates haematopoietic stem and progenitor cell specification

C Zhang, Y Chen, B Sun, LU Wang, Y Yang, D Ma, J Lv… - Nature, 2017 - nature.com
Abstract N 6-methyladenosine (m6A) has been identified as the most abundant modification
on eukaryote messenger RNA (mRNA). Although the rapid development of high-throughput …

N6-methyladenosine sequencing highlights the involvement of mRNA methylation in oocyte meiotic maturation and embryo development by regulating translation in …

ST Qi, JY Ma, ZB Wang, L Guo, Y Hou… - Journal of Biological …, 2016 - ASBMB
During the oogenesis of Xenopus laevis, oocytes accumulate maternal materials for early
embryo development. As the transcription activity of the oocyte is silenced at the fully grown …

METTL3‐Mediated m6A Methylation Regulates Muscle Stem Cells and Muscle Regeneration by Notch Signaling Pathway

Y Liang, H Han, Q Xiong, C Yang, L Wang… - Stem cells …, 2021 - Wiley Online Library
The Pax7+ muscle stem cells (MuSCs) are essential for skeletal muscle homeostasis and
muscle regeneration upon injury, while the molecular mechanisms underlying muscle stem …

Genome-wide analysis of H3K27me3 in porcine embryonic muscle development

B Tan, S Wang, S Wang, J Zeng, L Hong… - Frontiers in Cell and …, 2021 - frontiersin.org
The trimethylation of histone H3 lysine 27 (H3K27me3) is one of the most important
chromatin modifications, which is generally presented as a repressive mark in various …

N 6-Methyladenosine (m6A) Methylation in mRNA with A Dynamic and Reversible Epigenetic Modification

R Wu, D Jiang, Y Wang, X Wang - Molecular Biotechnology, 2016 - Springer
Abstract N 6-methyladenosine (m 6 A) is the most abundant and reversible internal
modification ubiquitously occurring in eukaryotic mRNA, albeit the significant biological roles …

Genome-wide DNA Methylation Profiles and Their Relationships with mRNA and the microRNA Transcriptome in Bovine Muscle Tissue (Bos taurine)

YZ Huang, JJ Sun, LZ Zhang, CJ Li, JE Womack… - Scientific reports, 2014 - nature.com
DNA methylation is a key epigenetic modification in mammals and plays important roles in
muscle development. We sampled longissimus dorsi muscle (LDM) from a well-known elite …

Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig

J Liu, Y Zhu, GZ Luo, X Wang, Y Yue, X Wang… - Nature …, 2016 - nature.com
Abstract DNA N 6-methyldeoxyadenosine (6mA) is a well-known prokaryotic DNA
modification that has been shown to exist and play epigenetic roles in eukaryotic DNA. Here …

Epitranscriptomic analysis of m6A methylome after peripheral nerve injury

L Zhang, D Hao, P Ma, B Ma, J Qin, G Tian, Z Liu… - Frontiers in …, 2021 - frontiersin.org
N6-methyladenosine (m6A) is one of the most plentiful internal RNA modifications,
especially in eukaryotic messenger RNA (mRNA), which plays pivotal roles in the regulation …