Samul Extract Protects Against the H2O2-Induced Apoptosis of H9c2 Cardiomyoblasts via Activation of Extracellular Regulated Kinases (Erk) 1/2

C Park, HS So, SJ Kim, MJ Youn, BS Moon… - The American journal …, 2006 - World Scientific
Samul extract, containing Radix Rehmanniae, Radix Angelicae Gigantis, Radix Paeoniae,
and Rhizoma Cnidii, has been traditionally used for treatment of ischemic heart and brain …

Effect of Acori graminei Rhizoma on contractile dysfunction of ischemic and reperfused rat heart

M Kang, JH Kim, C Cho, HS Chung… - Biological and …, 2006 - jstage.jst.go.jp
Biol. Pharm. Bull. 29(3) 483—488 (2006) Page 1 Cardiac ischemia is a condition in which the
blood flow and oxygen supply to the heart muscle are lacking. Cardiac ischemia leads to angina …

[HTML][HTML] Mechanism of the protective effect of Yulangsan flavonoid on myocardial ischemia/reperfusion injury in rats

X Zhang, X Liang, X Lin, S Zhang, Z Huang… - Cellular Physiology and …, 2014 - karger.com
Aims: Effect and mechanism of Yulangsan flavonoid (YLSF) on rat myocardial
ischemia/reperfusion injury (MI/RI) has been investigated. Methods: Sprague-Dawley (SD) …

Indole-3-Carbinol (I3C) protects the heart from ischemia/reperfusion injury by inhibiting oxidative stress, inflammation, and cellular apoptosis in mice

Q Li, B Xia, J Wu, X Yuan, X Lu, C Huang… - Frontiers in …, 2022 - frontiersin.org
Strategies for treating myocardial ischemia in the clinic usually include re-canalization of the
coronary arteries to restore blood supply to the myocardium. However, myocardial …

Ginkgo biloba extract reducing myocardium cells apoptosis by regulating apoptotic related proteins expression in myocardium tissues

ZY Qiao, JH Huang, JW Ma, YW Xu, J Xie, HJ Liu… - Molecular biology …, 2014 - Springer
The Bax, cyt-c and caspase-3 proteins play an important role in regulating the myocardial
apoptosis. Although very little is known about the specific signal pathways modulated by …

Protective effect of berberine against cardiac ischemia/reperfusion injury by inhibiting apoptosis through the activation of Smad7

W Yao, X Wang, K Xiao - Molecular and Cellular Probes, 2018 - Elsevier
Berberine (BBR) is an isoquinnoline derivative alkaloid extracted from Rhizoma Coptidis
that has the potential to protect myocardial tissues from ischemia/reperfusion (I/R) injuries …

Comparative pharmacokinetics of quercitrin, astragalin, afzelin and taxifolin in plasma after oral administration of Polygonum orientale inflorescence in sham …

L Zheng, Y Li, Z Zhou, W Xiang, Z Gong, S Chen… - Xenobiotica, 2020 - Taylor & Francis
The study aimed to compare the pharmacokinetic properties of quercitrin, astragalin, afzelin
and taxifolin, four major bioactive components of Polygonum orientale inflorescence …

Carvacrol protects against acute myocardial infarction of rats via anti-oxidative and anti-apoptotic pathways

W Yu, Q Liu, S Zhu - Biological and Pharmaceutical Bulletin, 2013 - jstage.jst.go.jp
Carvacrol (CAR), a naturally occurring phenolic monoterpene, has been shown to possess
diverse biological activities. The present study was undertaken to evaluate the …

Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress

G Zhao, L Yu, W Gao, W Duan, B Jiang, X Liu… - Acta Pharmacologica …, 2016 - nature.com
Aim: Berberine (BBR), an isoquinoline-derived alkaloid isolated from Rhizoma coptidis,
exerts cardioprotective effects. Because endoplasmic reticulum (ER) stress plays a pivotal …

Total flavones of Rhododendron simsii Planch flower protect isolated rat heart from ischaemia-reperfusion injury and its mechanism of UTR-RhoA-ROCK pathway …

XQ Sun, S Chen, LF Wang… - Journal of Pharmacy and …, 2018 - academic.oup.com
Abstract Objectives Total flavones of Rhododendron simsii Planch flower (TFR) are an
effective part extracted from the flower. The present study was designed to investigate the …