Rab3A deletion selectively reduces spontaneous neurotransmitter release at the mouse neuromuscular synapse

MS Sons, JJ Plomp - Brain research, 2006 - Elsevier
Rab3A is a synaptic vesicle-associated GTP-binding protein thought to be involved in
modulation of presynaptic transmitter release through regulation of vesicle trafficking and …

Rab3a deletion reduces vesicle docking and transmitter release at the mouse diaphragm synapse

WL Coleman, CA Bill, M Bykhovskaia - Neuroscience, 2007 - Elsevier
Rab3a is a small GTP binding protein associated with presynaptic vesicles that is thought to
regulate vesicle targeting to active zones. Although this rab3a function implies that vesicle …

Rab3a-mediated vesicle recruitment regulates short-term plasticity at the mouse diaphragm synapse

WL Coleman, M Bykhovskaia - Molecular and Cellular Neuroscience, 2009 - Elsevier
Rab3a is a small GTP-binding protein associated with presynaptic vesicles. We have
measured the releasable pool in the neuromuscular junction of Rab3a (−) mice by …

Regulation by Rab3A of an endogenous modulator of neurotransmitter release at mouse motor nerve endings

JK Hirsh, TJ Searl, EM Silinsky - The Journal of Physiology, 2002 - Wiley Online Library
Rab3A, a small GTP‐binding protein attached to synaptic vesicles, has been implicated in
several stages in the process of neurosecretion, including a late stage occurring just prior to …

Rabphilin knock-out mice reveal that rabphilin is not required for rab3 function in regulating neurotransmitter release

OM Schlüter, E Schnell, M Verhage… - Journal of …, 1999 - Soc Neuroscience
Rab3A and rab3C are GTP-binding proteins of synaptic vesicles that regulate vesicle
exocytosis. Rabphilin is a candidate rab3 effector at the synapse because it binds to rab3s in …

Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction

M Tanaka, J Miyoshi, H Ishizaki, A Togawa… - Molecular biology of …, 2001 - Am Soc Cell Biol
The Rab3 small G protein family consists of four members, Rab3A,-3B,-3C, and-3D. Of these
members, Rab3A regulates Ca2+-dependent neurotransmitter release. These small G …

Rab3a is involved in transport of synaptic vesicles to the active zone in mouse brain nerve terminals

AGM Leenders, FHL da Silva… - Molecular biology of …, 2001 - Am Soc Cell Biol
The rab family of GTP-binding proteins regulates membrane transport between intracellular
compartments. The major rab protein in brain, rab3A, associates with synaptic vesicles …

Impaired activity-dependent plasticity of quantal amplitude at the neuromuscular junction of Rab3A deletion and Rab3A earlybird mutant mice

X Wang, Q Wang, S Yang, M Bucan… - Journal of …, 2011 - Soc Neuroscience
Rab3A is a small GTPase associated with synaptic vesicles that is required for some forms
of activity-dependent plasticity. It is thought to regulate the number of vesicles that fuse …

A complete genetic analysis of neuronal Rab3 function

OM Schlüter, F Schmitz, R Jahn… - Journal of …, 2004 - Soc Neuroscience
Rab3A, Rab3B, Rab3C, and Rab3D are closely related GTP-binding proteins of synaptic
vesicles that may function in neurotransmitter release. We have produced knock-out (KO) …

Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release

T Wucherpfennig, M Wilsch-Bräuninger… - The Journal of cell …, 2003 - rupress.org
During constitutive endocytosis, internalized membrane traffics through endosomal
compartments. At synapses, endocytosis of vesicular membrane is temporally coupled to …