[HTML][HTML] Clinical efficacy of subgingivally delivered simvastatin gel in chronic periodontitis patients

S Agarwal, KK Chaubey, A Chaubey… - Journal of Indian …, 2016 - journals.lww.com
Background: Simvastatin (SMV), a new locally delivered drug of class statins, is a specific
competitive inhibitor of 3-hydroxy-2-methyl-glutaryl coenzyme A reductase. Statins, besides …

Clinical Eficacy of Subgingivally Delivered 1.2 mg Simvastatin in the Treatment of Patients with Aggressive Periodontitis: A Randomized Controlled Clinical Trial.

N Priyanka, A Abhilash, S Saquib… - … of Periodontics & …, 2017 - search.ebscohost.com
Simvastatin (SMV) is a specific competitive inhibitor of 3-hydroxy-2-methylglutaryl coenzyme
A reductase that promotes bone formation. The present clinical trial was designed to …

Efficacy of subgingivally delivered simvastatin in the treatment of patients with type 2 diabetes and chronic periodontitis: A randomized double‐masked controlled …

AR Pradeep, NS Rao, P Bajaj… - Journal of …, 2013 - Wiley Online Library
Background: Simvastatin (SMV) is a specific competitive inhibitor of 3‐hydroxy‐2‐methyl‐
glutaryl coenzyme A reductase. Recently, it has been reported that statins promote bone …

Clinical effect of subgingivally delivered simvastatin in the treatment of patients with chronic periodontitis: a randomized clinical trial

AR Pradeep, MS Thorat - Journal of periodontology, 2010 - Wiley Online Library
Background: Periodontitis is an inflammatory disease that results in bone resorption creating
bony defects, which may cause tooth loss. Various drugs have been studied using local …

Simvastatin local drug delivery in smokers with chronic periodontitis: a randomized controlled clinical trial

NS Rao, AR Pradeep, P Bajaj, M Kumari… - Australian dental …, 2013 - Wiley Online Library
Background Simvastatin (SMV) is a specific competitive inhibitor of 3‐hydroxy‐2‐methyl‐
glutaryl coenzyme A reductase. Statins have recently been shown to promote bone …

A clinical, radiological and IL-6 evaluation of subgingivally delivered simvastatin in the treatment of chronic periodontitis

A Rath, J Mahenra, L Thomas… - … Journal of Drug …, 2012 - search.proquest.com
Simvastatin (SMV) are specific competitive inhibitors which are widely used to lower
cholesterol for the treatment of hyperlipidemia and arteriosclerosis. They have shown to …

[HTML][HTML] Efficacy of locally administered 1.2% rosuvastatin gel in patients with periodontitis: a randomized placebo controlled clinical trial

D Chatterjee, A Kapoor, S Vijay, G Sobti… - European Journal of …, 2019 - thieme-connect.com
Objective Periodontitis initiation and progression are a result of host immune inflammatory
response to oral pathogens. Several pharmacological agents are being delivered locally, to …

[HTML][HTML] Sub-gingival delivery of simvastatin and rosuvastatin for treatment of chronic periodontitis with diabetes mellitus: A randomized controlled clinical-radiographic …

P Sharma, A Singh, S Mallapragada - Journal of Oral Biology and …, 2023 - Elsevier
Background Statins are lipid-lowering medications that work by blocking rate-limiting
enzyme in cholesterol formation. In patients with Chronic periodontitis (CP) and Diabetes …

Comparative evaluation of subgingivally delivered 1.2% rosuvastatin and 1% metformin gel in treatment of intrabony defects in chronic periodontitis: a randomized …

D Pankaj, I Sahu, IG Kurian… - Journal of …, 2018 - Wiley Online Library
Background The aim of this study is to explore and compare the clinical efficacy of locally
delivered 1.2% Rosuvastatin (RSV) and 1% Metformin (MF) gel as an adjunct to scaling and …

[HTML][HTML] Comparative evaluation of efficacy of subgingivally delivered 1.2% Atorvastatin and 1.2% Simvastatin in the treatment of intrabony defects in chronic …

SS Martande, M Kumari, AR Pradeep… - Journal of Dental …, 2017 - ncbi.nlm.nih.gov
Background. Statins are the recently evolved agents that aid in periodontal regeneration and
ultimately in attaining periodontal health. Atorvastatin (ATV) and Simvastatin (SMV) are …