The aim of this study was to detect characteristic structural changes in the cartilage
composition of osteoarthritis (OA), hereby improving the arthroscopic identification of …

BACKGROUND: Characteristic changes in cartilage of human knee joints with different
degrees of osteoarthritis (OA) have been investigated by visual, biophotonical and …

Osteoarthritis degenerates cartilage and impairs joint function. Early intervention
opportunities are missed as current diagnostic methods are insensitive to early tissue …

Damage to hyaline cartilage is the most important pathophysiological tool in the
development of osteoarthritis. Cartilage lesions are the most frequent pathological findings …

Purpose To develop the means to estimate cartilage histologic grades and proteoglycan
content in ex vivo arthroscopy using near-infrared spectroscopy (NIRS). Methods In this …

A non-destructive, diffuse reflectance near infrared spectroscopy (DR-NIRS) approach is
considered as a potential tool for determining the component-level structural properties of …

Background Arthroscopy is a highly sensitive method of evaluating high-grade cartilage
lesions but the detection of low-grade lesions is often is unreliable. Objective measurements …

Osteoarthritis (OA) is one of the most common joint diseases worldwide. Unfortunately,
clinical methods lack the ability to detect OA in the early stages. Timely detection of the knee …

OBJECTIVE: The aim of this study was to demonstrate the potential of near-infrared (NIR)
spectroscopy for categorizing cartilage degeneration induced in animal models. METHOD …

We have previously described a technology based on diffuse reflectance of broadband light
for measuring joint articular cartilage thickness, utilizing that optical absorption is different in …