AMP-activated protein kinase has been described as a key signaling protein that can
regulate energy homeostasis. Here, we aimed to characterize novel AMP-activated kinase …

The rising incidence of type 2 diabetes mellitus (T2DM) is a major public health problem and
novel therapeutic strategies are required to prevent and treat T2DM. It has been …

Myocardial contractile dysfunction in diabetic cardiomyocytes is a significant promoter of
heart failure. Herein, we investigated the effect of icariin, a flavonoid monomer isolated from …

Insulin resistance (IR) is the primary pathogenesis of Type 2 diabetes mellitus (T2DM).
Scutellaria baicalensis Georgi is a traditional Chinese herbal medicine, often used in the …

Berberine is a plant alkaloid with anti-diabetic action. Activation of AMP-activated protein
kinase (AMPK) pathway has been proposed as mechanism for berberine's action. This study …