Advances in our understanding of the mechanisms of proteinuria in humans have depended
on a variety of animal models. Most of these have been partially satisfactory because they …

Two brothers with nephrotic syndrome are reported. Their parents were first cousins. The
nephrotic syndrome developed at the age of 14 and 15 years and was resistant to the …

A form of spontaneous nephrosis characterized by proteinuria, hyperglobulinemia and
hypercholesterolemia occurs in the Sprague-Dawley rat. Proteinuria exists at weaning, and …

There seems to be little doubt that FGS is a nonspecific lesion that represents one way in
which the renal glomerulus responds to a variety of injuries. This is illustrated by the large …

Ten adults with the nephrotic syndrome and sterile pyuria are described. On biopsy they had
varying degrees of glomerular sclerosis without proliferation. Interstitial inflammation and …

Renal biopsy material from seven cases of the nephrotic syndrome due to focal glomerular
sclerosis has been studied by light, electron, and immunofluorescent microscopy. The …

THE nephrotic syndrome, a clinical entity characterized by edema, proteinuria,
hypoalbuminemia and hypercholesterolemia, may occur in the adult during the course of …

In this report, we describe the case of a boy who developed the nephrotic syndrome at one
and one-half years of age, remained steroid-responsive for nine years, but then became …

SUMMARY A survey of renal biopsies of Si patients with the nephrotic syndrome not due to
lupus erythematosus, renal amyloidosis, diabetic glomerulosclerosis or one of the …

A case of renal disease in a dog resembling human focal segmental glomerulosclerosis is
presented. A kidney biopsy from this animal showed focal glomerular sclerosis, with variable …