Sensory stimuli with graded intensities often lead to yes-or-no decisions on whether to
respond to the stimuli. How this graded-to-binary conversion is implemented in the central …

Nociception is an evolutionarily conserved mechanism to encode and process harmful
environmental stimuli. Like most animals, Drosophila melanogaster larvae respond to a …

Organisms rely on nociceptive sensory neurons to detect and avoid potentially tissue-
damaging stimuli in the environment. New research has unraveled previously unknown …

Animals' response to a stimulus in one sensory modality is usually influenced by other
modalities. 1 One important type of multisensory integration is the cross-modal modulation …

The mammalian brain implements sophisticated sensory processing algorithms along
multilayered (“deep”) neural networks. Strategies that insects use to meet similar …

Categorical neural responses underlie various forms of selection and decision-making.
Such binary-like responses promote robust signaling of the winner in the presence of input …

To ensure their survival, animals must be able to respond adaptively to threats within their
environment. However, the precise neural circuit mechanisms that underlie such flexible …

Feeding decisions are fundamental to survival, and decision making is often disrupted in
disease. Here, we show that neural activity in a small population of neurons projecting to the …

All organisms react to noxious and mechanical stimuli but we still lack a complete
understanding of cellular and molecular mechanisms by which somatosensory information …

In the natural world, animals make decisions on an ongoing basis, continuously selecting
which action to undertake next. In the lab, however, the neural bases of decision processes …