Fractional flow reserve is the current invasive gold standard for assessing the ischemic
potential of an angiographically intermediate coronary stenosis. Procedural cost and time …

Coronary angiography remains far and away the most accurate morphologic assessment of
the lumen of the epicardial coronary arteries. Although non-invasive imaging is rapidly …

Evidence robustly demonstrates that ischemia, rather than anatomy, is the optimal target for
coronary revascularization. In the cardiac catheter laboratory, fractional flow reserve (FFR) …

Revascularization of ischemia‐producing coronary lesions is widely used in the
management of coronary artery disease. However, some coronary lesions appear significant …

Pressure wire–based fractional flow reserve is considered the standard of reference for
evaluation of the ischemic potential of coronary stenoses and the expected benefit from …

Fractional flow reserve (FFR) and instantaneous wave-free ratio are the present standard
diagnostic methods for invasive assessment of the functional significance of epicardial …

Documentation of inducible myocardial ischaemia, related to the coronary stenosis of
interest, is of increasing importance in lesion selection for percutaneous coronary …

With growing numbers of patients with acute coronary syndromes undergoing
catheterization without prior non-invasive imaging and the increasing numbers of patients …

Evaluation of new coronary devices and demonstration of their conformity to essential
principles of safety and effectiveness requires clinical trials in human subjects. Today, many …

Abstract Purpose of Review Three-dimensional quantitative coronary angiography-based
methods of fractional flow reserve (FFR) derivation have emerged as an appealing …