Muscarinic and α1-adrenergic mechanisms contribute to the spinal mediation of stimulation-induced antinociception from the pedunculopontine tegmental nucleus in …

QM Dias, SF Crespilho, JWS Silveira… - … Biochemistry and Behavior, 2009 - Elsevier
The effects of intraperitoneal (ip) or intrathecal (it) injection of antagonists of acetylcholine,
noradrenaline, serotonin, dopamine, opioids and GABA on stimulation-produced …

Sequential mediation of norepinephrine-and dopamine-induced antinociception at the spinal level: involvement of different local neuroactive substances

S Yang, C Zhang, ZH Zhang, JT Qiao, N Dafny - Brain research bulletin, 1996 - Elsevier
The effects of intrathecally (it) administered opioid antagonist naloxone (Nal), adenosine
antagonist aminophylline (Aph), and γ-aminobutyric acid (GABAA)-receptor antagonist …

Spinal pharmacology of antinociception produced by microinjection of μ or δ opioid receptor agonists in the ventromedial medulla of the rat

RW Hurley, P Banfor, DL Hammond - Neuroscience, 2003 - Elsevier
This study examined the role of spinal GABAergic, serotoninergic and α2 adrenergic
receptors in the antinociception produced by the microinjection of equi-antinociceptive …

Characterization of inhibition of a spinal nociceptive reflex by stimulation medially and laterally in the midbrain and medulla in the pentobarbital-anesthetized rat

J Sandkühler, GF Gebhart - Brain research, 1984 - Elsevier
Inhibition of the spinal nociceptive tail flick (TF) reflex by electrical stimulation throughout the
midbrain and medulla was examined and characterized in pentobarbital-anesthetized rats …

Contribution of spinal inhibitory receptors in heterosegmental antinociception induced by noxious stimulation

CH Tambeli, P Quang, JD Levine… - European Journal of …, 2003 - Wiley Online Library
Noxious (ie painful) stimulation in the rat induces profound heterosegmental antinociception
as demonstrated by the ability of either thermal stimulation (50° C water) or subdermal …

[HTML][HTML] Stimulation-produced analgesia from the occipital or retrosplenial cortex of rats involves serotonergic and opioid mechanisms in the anterior pretectal nucleus

GM Reis, AC Rossaneis, JWS Silveira, QM Dias… - The Journal of …, 2011 - Elsevier
The electrical stimulation of the occipital (OC) or retrosplenial (RSC) cortex produces
antinociception in the rat tail-flick test. These cortices send inputs to the anterior pretectal …

Antinociception induced by intravenous dipyrone (metamizol) upon dorsal horn neurons: involvement of endogenous opioids at the periaqueductal gray matter, the …

E Vazquez, N Hernandez, W Escobar, H Vanegas - Brain research, 2005 - Elsevier
Microinjection of dipyrone (metamizol) into the periaqueductal gray matter (PAG) in rats
causes antinociception. This is mediated by endogenous opioidergic circuits located in the …

Role of spinal δ1 and δ2 opioid receptors in the antinociception produced by microinjection of l-glutamate in the ventromedial medulla of the rat

DL Hammond, BB Donahue, PE Stewart - Brain research, 1997 - Elsevier
This study examined the contribution of spinal δ1 and δ2 opioid receptors to the
antinociception produced by microinjection of l-glutamate in either the nucleus raphe …

[HTML][HTML] Neural correlates of the antinociceptive effects of stimulating the anterior pretectal nucleus in rats

K Genaro, WA Prado - The Journal of Pain, 2016 - Elsevier
Stimulation-evoked antinociception (SEA) from the anterior pretectal nucleus (APtN)
activates mechanisms that descend to the spinal cord through the dorsolateral funiculus, but …

Opiate-like substances mediate norepinephrine-induced but not serotonin-induced antinociception at spinal level Reevaluation by an electrophysiological model of …

J Ma, J Qiao, N Dafny - Life Sciences, 2001 - Elsevier
After subcutaneous injection of formalin (5%, 50 μl) into a hindpaw of rats, biphasic
excitatory nociceptive discharges were recorded extracellularly in thalamic parafascicular …