The tiny big world of solid lipid nanoparticles and nanostructured lipid carriers: an updated review

HM Abdel-Mageed, AE Abd El Aziz… - Journal of …, 2022 - Taylor & Francis
Nanotechnology is currently a field of endeavour that has reached a maturation phase
beyond the initial hypotheses with an undercurrent challenge to optimise the safety, and …

Nanostructured lipid carriers-mediated brain delivery of carbamazepine for improved in vivo anticonvulsant and anxiolytic activity

N Khan, FA Shah, I Rana, MM Ansari, F ud Din… - International journal of …, 2020 - Elsevier
The limited brain delivery of carbamezapine (CBZ) presents a major hurdle in the successful
epilepsy treatment. The potential of carbamezapine-loaded nanostructured lipid carriers …

Nanostructured lipid carriers engineered for intranasal delivery of teriflunomide in multiple sclerosis: optimization and in vivo studies

DG Gadhave, CR Kokare - Drug development and industrial …, 2019 - Taylor & Francis
Background: Multiple sclerosis (MS) is one of the most severe autoimmune disorder of the
central nervous system (CNS). Objective: The present research work was aimed to formulate …

[HTML][HTML] Nanostructured lipid carriers: An emerging platform for improving oral bioavailability of lipophilic drugs

S Khan, S Baboota, J Ali, S Khan… - International journal …, 2015 - ncbi.nlm.nih.gov
Nowadays exploration of novel lipid-based formulations is akin to a magnet for researchers
worldwide for improving the in vivo performance of highly lipophilic drugs. Over the last few …

[HTML][HTML] Solid lipid nanoparticles for targeted natural and synthetic drugs delivery in high-incidence cancers, and other diseases: Roles of preparation methods, lipid …

HA Mohammed, RA Khan, V Singh, M Yusuf… - Nanotechnology …, 2023 - degruyter.com
Solid lipid nanoparticles (SLNs), the spheroidal-shaped, colloids state lipophilic-natured,
innovative nanoscale particulate materials, are being concurrently prepared by the quality …

Lipid based drug delivery systems for oral, transdermal and parenteral delivery: recent strategies for targeted delivery consistent with different clinical application

AK Srivastav, S Karpathak, MK Rai, D Kumar… - Journal of Drug Delivery …, 2023 - Elsevier
Lipid based drug delivery systems (LBDDS) are valuable and biocompatible nano-carriers
for the vehiculation and potential delivery of various hydrophilic, hydrophobic, or amphiphilic …

Liposomes for brain delivery

F Lai, AM Fadda, C Sinico - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: Development of drug delivery systems for brain delivery is one of the most
challenging research topics in pharmaceutical areas, mainly due to the presence of the …

[HTML][HTML] Perspectives and prospective on solid lipid nanoparticles as drug delivery systems

OA Madkhali - Molecules, 2022 - mdpi.com
Combating multiple drug resistance necessitates the delivery of drug molecules at the
cellular level. Novel drug delivery formulations have made it possible to improve the …

ApoE-modified solid lipid nanoparticles: A feasible strategy to cross the blood-brain barrier

R Dal Magro, F Ornaghi, I Cambianica, S Beretta… - Journal of Controlled …, 2017 - Elsevier
Solid lipid nanoparticles (SLN) are colloidal drug delivery systems characterized by higher
entrapment efficiency, good scalability of the preparation process and increased sustained …

The blood-brain barrier and brain drug delivery

JM Koziara, PR Lockman, DD Allen… - … of nanoscience and …, 2006 - ingentaconnect.com
The present report encompasses a thorough review of drug delivery to the brain with a
particular focus on using drug carriers such as liposomes and nanoparticles. Challenges in …