Abstract Fibroblast growth factor 23 (FGF23), one of the endocrine fibroblast growth factors,
is a principal regulator in the maintenance of serum phosphorus concentration. Binding to its …

Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23.
Background The gene for the renal phosphate wasting disorder autosomal-dominant …

There is a discontinuum of hereditary and acquired disorders of phosphate homeostasis that
are caused by either high or low circulating levels of the novel phosphaturic hormone …

Rickets in the growing child or adolescent and osteomalacia in the adult develop in a variety
of clinical situations and have in common an absence or delay in the mineralization of …

AIM To describe 21 cases of symptomatic rickets in adolescents. METHODS The setting was
a primary and secondary care hospital in Saudi Arabia providing medical care to Saudi Arab …

Autosomal dominant hypophosphatemic rickets (ADHR) is unique among the disorders
involving Fibroblast growth factor 23 (FGF23) because individuals with R176Q/W and …

ABSTRACT FGF23 is an important hormonal regulator of phosphate homeostasis. Together
with its co receptor Klotho, it modulates phosphate reabsorption and both 1α hydroxylation …

Abstract Fibroblast growth factor-23 (FGF23) regulates phosphate reabsorption in the kidney
and therefore plays an essential role in phosphate balance in humans. There is a host of …

The metabolic changes that occur in patients with chronic kidney disease (CKD) have a
profound influence on mineral and bone metabolism. CKD results in altered levels of serum …

Objective To determine temporal trends in incidence and risk factors of nutritional rickets in a
community-based population. Patients and Methods Rochester Epidemiology Project data …