Background Inhaled corticosteroids (ICS) are the first-line therapy in the treatment of
persistent asthma. At medium to high doses and prolonged usage, ICS can supresss the …

Objective To describe two clinical cases of systemic side effects from use of fluticasone
nasal spray. Methods A retrospective review of medical records of two patients using this …

Inhaled corticosteroids (ICS) have been used as first line treatment of asthma for many
decades. ICS are a form of exogenous glucocorticosteroids that can suppress the …

Abstract Hypothalamus-Pituitary-Adrenal (HPA) may be disturbed by drugs, including
opioids. In fact, opioids are a well-recognized cause of hypogonadotropic hypogonadism …

OBJECTIVE: To report the rapid onset of adrenal insufficiency and subsequent development
of Cushing syndrome precipitated by a CYP3A4-mediated drugdrug interaction that may …

Study objective: This study was conducted to compare the adrenal suppression of inhaled
fluticasone propionate and triamcinolone acetonide in healthy volunteers, both given via …

We report on a 64-year-old patient in whom fentanyl therapy was found to be responsible for
the induction of secondary adrenal insufficiency as clearly demonstrated by re-exposure. We …

Inhaled corticosteroids (ICS) are drugs of choice for persistent asthma. Less than 500 µg/d of
fluticasone are believed to be safe. We found 92 cases of adrenal suppression in PubMed; …

Objective: Adrenal insufficiency (AI) is a potentially life-threatening condition. It is known that
high doses of inhaled corticosteroids (ICS) can induce systemic adverse effects. Currently …

Background: Inhaled corticosteroids are the mainstay of therapy for persistent asthma and
are quite safe. Recently, however, studies have demonstrated that these agents can be …