Natural indole‐containing alkaloids and their antibacterial activities

Y Liu, Y Cui, L Lu, Y Gong, W Han… - Archiv der …, 2020 - Wiley Online Library
As the growth in resistance to bacterial infection treatments poses a grave threat to global
health in the 21st century, there is a constant need to explore novel antibacterial agents that …

[HTML][HTML] Research progress on antibacterial activities and mechanisms of natural alkaloids: A review

Y Yan, X Li, C Zhang, L Lv, B Gao, M Li - Antibiotics, 2021 - mdpi.com
Alkaloids are nitrogen-containing heterocyclic compounds typically isolated from plants.
They represent one of the most important types of natural products because of their large …

The natural and synthetic indole weaponry against bacteria

MG Ciulla, K Kumar - Tetrahedron letters, 2018 - Elsevier
The emergence of drug resistant bacterial infections leading to high mortality rates has
posed a formidable challenge to organic synthesis and medicinal chemists to deliver potent …

Indole/isatin‐containing hybrids as potential antibacterial agents

F Song, Z Li, Y Bian, X Huo, J Fang… - Archiv der …, 2020 - Wiley Online Library
The emergence and worldwide spread of drug‐resistant bacteria have already posed a
serious threat to human life, creating the urgent need to develop potent and novel …

Plant-derived natural alkaloids as new antimicrobial and adjuvant agents in existing antimicrobial therapy

RP Mittal, V Jaitak - Current Drug Targets, 2019 - ingentaconnect.com
Infectious diseases, instigated by pathogenic microorganisms are the cause of numerous
health problems in developing countries. Infectious diseases got a place in the list of top ten …

Indole and indoline scaffolds in antimicrobials: Overview, synthesis and recent advances in antimicrobial research

MJ Nieto, HK Lupton - Current Medicinal Chemistry, 2021 - ingentaconnect.com
At present, a pandemic of antibiotic-resistant infectious diseases is an evergrowing threat.
The need for new antibiotics and ways to combat antibiotic resistance is glaring. This review …

[HTML][HTML] Naturally-occurring alkaloids of plant origin as potential antimicrobials against antibiotic-resistant infections

B Casciaro, L Mangiardi, F Cappiello, I Romeo… - Molecules, 2020 - mdpi.com
Antibiotic resistance is now considered a worldwide problem that puts public health at risk.
The onset of bacterial strains resistant to conventional antibiotics and the scarcity of new …

Indole alkaloids from marine sources as potential leads against infectious diseases

PHB Franca, DP Barbosa, DL da Silva… - BioMed research …, 2014 - Wiley Online Library
Indole alkaloids comprise a large and complex class of natural products found in a variety of
marine sources. Infectious diseases remain a major threat to public health, and in the …

Synergy Potential of Indole Alkaloids and Its Derivative against Drug‐resistant Escherichia coli

GR Dwivedi, S Gupta, A Maurya… - Chemical Biology & …, 2015 - Wiley Online Library
Antibacterial and synergy potential of naturally occurring indole alkaloids (IA): 10‐methoxy
tetrahydroalstonine (1), isoreserpiline (2), 10 and 11 demethoxyreserpiline (3), reserpiline …

[HTML][HTML] Isolation and Antibacterial Activity of Indole Alkaloids from Pseudomonas aeruginosa UWI-1

A Ramkissoon, M Seepersaud, A Maxwell… - Molecules, 2020 - mdpi.com
In this study, we report the first isolation of three antibiotic indole alkaloid compounds from a
Pseudomonad bacterium, Pseudomonas aeruginosa UWI-1. The bacterium was batch …