Antimicrobial discovery from natural and unusual sources

SM Ali, R Siddiqui, NA Khan - Journal of Pharmacy and …, 2018 - academic.oup.com
Objectives Whether vertebrates/invertebrates living in polluted environments are an
additional source of antimicrobials. Key findings Majority of antimicrobials have been …

Antimicrobial natural products: an update on future antibiotic drug candidates

M Saleem, M Nazir, MS Ali, H Hussain, YS Lee… - Natural product …, 2010 - pubs.rsc.org
Covering: 2000 to 2008 Over the last decade, it has become clear that antimicrobial drugs
are losing their effectiveness due to the evolution of pathogen resistance. There is therefore …

Plant-derived antimicrobials to fight against multi-drug-resistant human pathogens

R Subramani, M Narayanasamy, KD Feussner - 3 Biotech, 2017 - Springer
Antibiotic resistance is becoming a pivotal concern for public health that has accelerated the
search for new antimicrobial molecules from nature. Numbers of human pathogens have …

Synthesis and biological evaluation of indole-based peptidomimetics as antibacterial agents against Gram-positive bacteria

Y Chen, H Li, J Liu, R Zhong, H Li, S Fang, S Liu… - European Journal of …, 2021 - Elsevier
The emergence of bacterial multidrug resistance and the lack of new antimicrobial agents
urgently demand the discovery and development of novel antibacterials that avoid bacterial …

Novel antibacterial compounds and their drug targets-successes and challenges

AA Kaczor, A Polski, K Sobótka-Polska… - Current medicinal …, 2017 - ingentaconnect.com
Infectious diseases are one of the most important and urgent health problems in the world.
According to the World Health Organization (WHO) statistics, infectious and parasitic …

[HTML][HTML] Isatin Bis-Indole and Bis-Imidazothiazole hybrids: synthesis and antimicrobial activity

F Bonvicini, A Locatelli, R Morigi, A Leoni… - Molecules, 2022 - mdpi.com
Isatin and its derivatives are important heterocycles found in nature and present in
numerous bioactive compounds which possess various biological activities. Moreover, it is …

Empirical antibacterial drug discovery—Foundation in natural products

SB Singh, JF Barrett - Biochemical pharmacology, 2006 - Elsevier
Natural products have been a rich source in providing leads for the development of drugs for
the treatment of bacterial infections. However, beyond the discovery of the natural product …

[HTML][HTML] Antimicrobial activities and mechanisms of extract and components of herbs in East Asia

J Liang, X Huang, G Ma - RSC advances, 2022 - pubs.rsc.org
Antibacterial drugs face increasing challenges due to drug resistance and adverse
reactions, which has created a pressing need for the discovery and development of novel …

[HTML][HTML] Antimicrobial compounds from microorganisms

C Amaning Danquah, PAB Minkah, I Osei Duah Junior… - Antibiotics, 2022 - mdpi.com
Antimicrobial resistance is an exigent public health concern owing to the emergence of
novel strains of human resistant pathogens and the concurrent rise in multi-drug resistance …

Novel antibacterial agents: an emergent need to win the battle against infections

NG Simoes, AF Bettencourt, N Monge… - Mini Reviews in …, 2017 - ingentaconnect.com
Background: Multiple strategies have been recommended for prevention and control of
antibacterial resistance. Solutions will need to be found soon if we are not to run the serious …