Experimental studies showed that genomic imprinting is fundamental in fetoplacental
development by timely regulating the expression of the imprinted genes to overlook a set of …

The importance of imprinted genes in regulating feto-placental development has been long
established. However, a comprehensive assessment of the role of placental imprinted gene …

Genomic imprinting is essential for normal placental and fetal growth. One theory to explain
the evolution of imprinting is the kinship theory (KT), which predicts that genes that are …

As a field of study, genomic imprinting has grown rapidly in the last 20 years, with a growing
figure of around 100 imprinted genes known in the mouse and approximately 50 in the …

OBJECTIVE: The purpose of this study was to investigate imprinting patterns in first-trimester
human placentas. STUDY DESIGN: Using samples of 17 first-trimester and 14 term …

Imprinted genes are expressed monoallelically depending on their parental origin. High
expression of the majority of imprinted genes tested to date has been demonstrated in …

The discovery of genomic imprinting through studies of manipulated mouse embryos
indicated that the paternal genome has a major influence on placental development …

Background Genomic imprinting, mediated by parent-of-origin-specific epigenetic silencing,
adjusts the gene expression dosage in mammals. We aimed to clarify parental allelic …

Identifying the genetic input for fetal growth will help to understand common, serious
complications of pregnancy such as fetal growth restriction. Genomic imprinting is an …

With the launch of the National Institute of Child Health and Human Development/National
Institutes of Health Human Placenta Project, the anticipation is that this often-overlooked …