Objective To investigate the role of glycogen metabolism in regulating rheumatoid fibroblast-
like synoviocyte (FLS)-mediated synovial inflammation and its underlying mechanism …

Objective Up‐regulation of glucose metabolism has been implicated not only in tumor cell
growth but also in immune cells upon activation. However, little is known about the …

Metabolomic studies show that rheumatoid arthritis (RA) is associated with metabolic
disruption that may be therapeutically targetable. Among them, glucose metabolism and …

Background The recent findings of cancer-specific metabolic changes, including increased
glucose and glutamine consumption, have provided new therapeutic targets for …

Glucose metabolism is considerably increased in inflamed joints of rheumatoid arthritis (RA)
patients at early stages. Fibroblast-like synoviocytes (FLSs) activation and subsequent joint …

Introduction Fibroblast-like synoviocytes (FLS) play an important role in the pathogenesis of
rheumatoid arthritis (RA). This study aimed to investigate the role of glucose 6-phosphate …

Glucose metabolism not only provides energy for physical activity but also mediates a
variety of physiological processes through the formation of complex signalling networks …

Objective This study aimed to evaluate glycolysis inhibitor which can effectively ameliorate
arthritis by inhibiting synoviocyte activation through AMPK/NF-кB pathway in AA rats …

Objectives Glycogen synthase kinase (GSK)-3β, a serine/threonine protein kinase, has been
implicated as a regulator of the inflammatory response. This study was performed to …

Background A dysregulated glucose metabolism in synovial fibroblasts (SF) has been
associated with their aggressive phenotype in rheumatoid arthritis (RA). Even though T …