Molecular and Genetic Basis of Pathogenesis in Francisella Tularensis
The genetic means of pathogenesis of Francisella tularensis are poorly understood. F.
tularensis is able to survive and replicate within macrophages, and a virulence factor, MglA …
tularensis is able to survive and replicate within macrophages, and a virulence factor, MglA …
The unraveling panoply of Francisella tularensis virulence attributes
KL Meibom, A Charbit - Current opinion in microbiology, 2010 - Elsevier
Francisella tularensis is a highly infectious Gram-negative bacterium causing the zoonotic
disease tularemia. This facultative intracellular pathogen multiplies in vivo mainly inside …
disease tularemia. This facultative intracellular pathogen multiplies in vivo mainly inside …
Francisella tularensis: unravelling the secrets of an intracellular pathogen
PCF Oyston - Journal of medical microbiology, 2008 - microbiologyresearch.org
Francisella tularensis has been recognized as the causative agent of tularaemia for almost a
century. Since its discovery in 1911, it has been shown to infect a wide range of hosts …
century. Since its discovery in 1911, it has been shown to infect a wide range of hosts …
Working toward the Future: Insights into Francisella tularensis Pathogenesis and Vaccine Development
RD Pechous, TR McCarthy… - … and molecular biology …, 2009 - Am Soc Microbiol
Francisella tularensis is a facultative intracellular gram-negative pathogen and the
etiological agent of the zoonotic disease tularemia. Recent advances in the field of …
etiological agent of the zoonotic disease tularemia. Recent advances in the field of …
A Francisella tularensis Pathogenicity Island Required for Intramacrophage Growth
Francisella tularensis is a gram-negative, facultative intracellular pathogen that causes the
highly infectious zoonotic disease tularemia. We have discovered a ca. 30-kb pathogenicity …
highly infectious zoonotic disease tularemia. We have discovered a ca. 30-kb pathogenicity …
Will the enigma of Francisella tularensis virulence soon be solved?
Francisella tularensis is one of the most infectious bacterial pathogens known and is the
causative agent of the zoonotic disease tularemia. In spite of the importance of this pathogen …
causative agent of the zoonotic disease tularemia. In spite of the importance of this pathogen …
Virulence determinants and protective antigens of Francisella tularensis
A Sjöstedt - Current opinion in microbiology, 2003 - Elsevier
Very little is known about virulence mechanisms of the highly virulent bacterium Francisella
tularensis. Specific genetic features of F. tularensis have been obstacles for the …
tularensis. Specific genetic features of F. tularensis have been obstacles for the …
Loops and networks in control of Francisella tularensis virulence
KL Meibom, M Barel, A Charbit - Future Microbiology, 2009 - Future Medicine
Francisella tularensis is a highly infectious, Gram-negative bacterium responsible for the
disease tularemia in a broad variety of animals, including humans. F. tularensis intracellular …
disease tularemia in a broad variety of animals, including humans. F. tularensis intracellular …
Identification of MglA-Regulated Genes Reveals Novel Virulence Factors in Francisella tularensis
The facultative intracellular bacterium Francisella tularensis causes the zoonotic disease
tularemia. F. tularensis resides within host macrophages in vivo, and this ability is essential …
tularemia. F. tularensis resides within host macrophages in vivo, and this ability is essential …
Modulation of virulence factors in Francisella tularensis determines human macrophage responses
PE Carlson Jr, JA Carroll, DM O'Dee, GJ Nau - Microbial pathogenesis, 2007 - Elsevier
Francisella tularensis, the causative agent of tularemia and Category A biodefense agent, is
known to replicate within host macrophages, though the pathogenesis of this organism is …
known to replicate within host macrophages, though the pathogenesis of this organism is …