Prediction of Ki-67 labeling index, ATRX mutation, and MGMT promoter methylation status in IDH-mutant astrocytoma by morphological MRI, SWI, DWI, and DSC-PWI
X Yang, C Hu, Z Xing, Y Lin, Y Su, X Wang, D Cao - European Radiology, 2023 - Springer
Objective Noninvasive detection of molecular status of astrocytoma is of great clinical
significance for predicting therapeutic response and prognosis. We aimed to evaluate …
significance for predicting therapeutic response and prognosis. We aimed to evaluate …
Magnetic resonance imaging derived biomarkers of IDH mutation status and overall survival in grade III astrocytomas
P Feraco, A Bacci, P Ferrazza, L Van den Hauwe… - Diagnostics, 2020 - mdpi.com
The evaluation of the isocitrate dehydrogenase (IDH) mutation status in the glioma decision-
making process has diagnostic, prognostic and therapeutic implications. The aim of this …
making process has diagnostic, prognostic and therapeutic implications. The aim of this …
Modelling MR and clinical features in grade II/III astrocytomas to predict IDH mutation status
Background and purpose There is increasing evidence that many IDH wildtype (IDH wt)
astrocytomas have a poor prognosis and although MR features have been identified, there …
astrocytomas have a poor prognosis and although MR features have been identified, there …
Prognostic stratification for IDH-wild-type lower-grade astrocytoma by Sanger sequencing and copy-number alteration analysis with MLPA
Y Makino, Y Arakawa, E Yoshioka, T Shofuda… - Scientific Reports, 2021 - nature.com
The characteristics of IDH-wild-type lower-grade astrocytoma remain unclear. According to
cIMPACT-NOW update 3, IDH-wild-type astrocytomas with any of the following factors show …
cIMPACT-NOW update 3, IDH-wild-type astrocytomas with any of the following factors show …
Noninvasive assessment of IDH mutational status in World Health Organization grade II and III astrocytomas using DWI and DSC-PWI combined with conventional MR …
Z Xing, X Yang, D She, Y Lin… - American Journal of …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Isocitrate dehydrogenase (IDH) has been shown to have
both diagnostic and prognostic implications in gliomas. The purpose of this study was to …
both diagnostic and prognostic implications in gliomas. The purpose of this study was to …
[HTML][HTML] Molecular markers related to patient outcome in patients with IDH-mutant astrocytomas grade 2 to 4: A systematic review
CMS Tesileanu, WR Vallentgoed, PJ French… - European Journal of …, 2022 - Elsevier
Background Grading and classification of IDH-mutant astrocytomas has shifted from solely
histology towards histology combined with molecular diagnostics. In this systematic review …
histology towards histology combined with molecular diagnostics. In this systematic review …
MRI based Radiomics for Distinguishing IDH-mutant from IDH wild-type Grade-4 Astrocytomas
SA Hosseini, I Shiri, G Hajianfar, S Bagley… - Proceedings of the …, 2022 - archive.ismrm.org
To distinguish IDH-mutant from IDH wild-type grade-4 astrocytomas, conventional MR
imaging (post-contrast T1-weighted and T2-Flair images) was acquired from 57 patients …
imaging (post-contrast T1-weighted and T2-Flair images) was acquired from 57 patients …
Grading of IDH-mutant astrocytoma using diffusion, susceptibility and perfusion-weighted imaging
X Yang, Z Xing, D She, Y Lin, H Zhang, Y Su… - BMC Medical Imaging, 2022 - Springer
Background The accurate grading of IDH-mutant astrocytoma is essential to make
therapeutic strategies and assess the prognosis of patients. The purpose of this study was to …
therapeutic strategies and assess the prognosis of patients. The purpose of this study was to …
Prognostic value of DNA methylation subclassification, aneuploidy, and CDKN2A/B homozygous deletion in predicting clinical outcome of IDH mutant astrocytomas
K Galbraith, M Garcia, S Wei, A Chen, C Schroff… - Neuro …, 2024 - academic.oup.com
Introduction IDH mutant astrocytoma grading, until recently, has been entirely based on
morphology. The 5th edition of the Central Nervous System WHO introduces CDKN2A/B …
morphology. The 5th edition of the Central Nervous System WHO introduces CDKN2A/B …
Correlating MRI features with additional genetic markers and patient survival in histological grade 2-3 IDH-mutant astrocytomas
Purpose The increasing importance of molecular markers for classification and
prognostication of diffuse gliomas has prompted the use of imaging features to predict …
prognostication of diffuse gliomas has prompted the use of imaging features to predict …