Mechanisms of action of nitric oxide in the brain stem: role of oxidative stress

J Zanzinger - Autonomic Neuroscience, 2002 - Elsevier
The exact mechanisms by which NO mediates its neuromodulatory effects within the central
control of cardiovascular functions are still unclear. Both excitatory and inhibitory actions of …

Control of systemic and pulmonary blood pressure by nitric oxide formed through neuronal nitric oxide synthase

N Toda, K Ayajiki, T Okamura - Journal of hypertension, 2009 - journals.lww.com
Nitric oxide formed by neuronal nitric oxide synthase (nNOS) in the brain, autonomic
inhibitory (nitrergic) nerves, and heart plays important roles in the control of blood pressure …

Neuronal nitric oxide synthase: structure, subcellular localization, regulation, and clinical implications

L Zhou, DY Zhu - Nitric oxide, 2009 - Elsevier
Nitric oxide (NO), a free gaseous signaling molecule, is involved in the regulation of the
cardiovascular, nervous and immune system. The neurotransmitter function of nitric oxide is …

Recent advances in the understanding of the role of nitric oxide in cardiovascular homeostasis

R Schulz, T Rassaf, PB Massion, M Kelm… - Pharmacology & …, 2005 - Elsevier
Nitric oxide synthases (NOS) are the enzymes responsible for nitric oxide (NO) generation.
To date, 3 distinct NOS isoforms have been identified: neuronal NOS (NOS1), inducible NOS …

Pathophysiological relevance of NO signaling in the cardiovascular system: novel insight from mice lacking all NO synthases

M Tsutsui, H Shimokawa, Y Otsuji… - Pharmacology & …, 2010 - Elsevier
Nitric oxide (NO) exerts a variety of biological actions under both physiological and
pathological conditions. NO is synthesized by three distinct NO synthase (NOS) isoforms …

Nitric oxide as a unique bioactive signaling messenger in physiology and pathophysiology

N Tuteja, M Chandra, R Tuteja… - BioMed Research …, 2004 - Wiley Online Library
Nitric oxide (NO) is an intra‐and extracellular messenger that mediates diverse signaling
pathways in target cells and is known to play an important role in many physiological …

Cardiovascular and renal control in NOS-deficient mouse models

PA Ortiz, JL Garvin - American Journal of Physiology …, 2003 - journals.physiology.org
Nitric oxide (NO) plays an essential role in the maintenance of cardiovascular and renal
homeostasis. Endogenous NO is produced by three different NO synthase (NOS) isoforms …

The role of nitric oxide in cardiovascular diseases

KM Naseem - Molecular aspects of medicine, 2005 - Elsevier
Nitric oxide (NO) is a gaseous lipophilic free radical cellular messenger generated by three
distinct isoforms of nitric oxide synthases (NOS), neuronal (nNOS), inducible (iNOS) and …

Neurobiology of nitric oxide

HY Yun, VL Dawson, TM Dawson - Critical Reviews™ in …, 1996 - dl.begellhouse.com
Nitric oxide is a ubiquitous and unique biological messenger molecule. It mediates blood
vessel relaxation by endothelium, immune function of macrophages, and neurotransmission …

Neuronal nitric oxide synthase as a novel anti-atherogenic factor

M Tsutsui - Journal of atherosclerosis and thrombosis, 2004 - jstage.jst.go.jp
Nitric oxide (NO) has multiple important actions that contribute to the maintenance of
vascular homeostasis. NO is synthesized by three different isoforms of NO synthase (NOS) …