Sleep disruption is a commonly encountered clinical feature in schizophrenic patients, and
one important concern is to determine the extent of this disruption under “real” life situations …

BackgroundSleep disturbances comparable with insomnia occur in up to 80% of people with
schizophrenia, but very little is known about the contribution of circadian coordination to …

Objective Aim of this study was to verify if a simple index as night-day plasma MLT level
variation is able to confirm the existing data on circadian melatonin alterations in …

Objective. The aim of this study was to compare the endogenous melatonin sleep-promoting
effect in schizophrenic patients to a sample of healthy controls. Methods. Thirty-four …

Background: Accumulating evidence indicates decreased melatonin levels in patients with
schizophrenia. Insomnia, mainly difficulty in falling asleep at night, is commonly reported in …

The 24-h profiles of plasma melatonin and cortisol were evaluated in 7 drug-free male
paranoid schizophrenics and in 7 healthy subjects matched to the patients for age, sex, body …

Patients with schizophrenia may have sleep disorders even when clinically stable under
antipsychotic treatments. To better understand this issue, we measured sleep characteristics …

The first-night effect (FNE) is the tendency for individuals to sleep worse than normal during
their first night of polysomnographic sleep evaluation. FNE reflects the adaptive increase of …

BackgroundIrregular sleep–wake cycles and cognitive impairment are frequently observed
in schizophrenia, however, how they interact remains unclear. AimsTo investigate the …

Twenty-four hour circadian activity rhythms and light-exposure levels of 28 older
schizophrenia patients (mean age= 58years) were examined using an Actillume recorder …