The aim of the study was to identify genetic variants associated with refined asthma
phenotypes enabling multiple features of the disease to be taken into account. Latent class …

There is a need to improve asthma characterisation by integrating multiple aspects of the
disease. The aim of the present study was to identify distinct asthma phenotypes by applying …

Rationale Asthma has substantial morbidity and mortality and a strong genetic component,
but identification of genetic risk factors is limited by availability of suitable studies. Objectives …

Objectives: There is evidence to suggest that asthma pathogenesis is affected by both
genetic and epigenetic variation independently, and there is some evidence to suggest that …

In the era of genome-wide association (GWA) studies, delineating pathogenic asthma
genetic pathways has provided both challenges and opportunities. Initial GWA studies on …

Background The extent of differences between genetic risks associated with various asthma
subtypes is still unknown. To better understand the heterogeneity of asthma, we employed …

Background Genomewide association study (GWAS) published by GABRIEL consortium
identified 10 asthma‐associated loci. However, their relationship with lung functions is …

Background Asthma and allergy are complex multifactorial disorders, with both genetic and
environmental components determining disease expression. The use of molecular genetics …

Asthma is a chronic and genetically complex respiratory disease that affects over 300 million
people worldwide. Here, we report a genome-wide analysis for asthma using data from the …

Background Susceptibility to asthma is influenced by genes and environment; implicated
genes may indicate pathways for therapeutic intervention. Genetic risk factors may be useful …